excruciation

1. Euthanasia is not yet legal in Japan, but given the excruciation suffering of patients with terminal cancer is terrible.
   安乐死在日本尚未合法，忍受癌症末期这种酷刑是很可怕的。
2. Excruciation in the Time of Transition: Heathendom and Tolerance& Research on Belief Tolerance before Religious Reform in England
   过渡时期的磨难：异端与宽容&英国宗教改革前的信仰宽容问题
3. "The children who have lost their parents probably could grow up; however, the parents who have been deprived of their kids will never come out of their grief." Some parents in China understand such excruciation than anyone else.
   失去父母的孩子或许可以长大，但失去孩子的父母却永远无法走出来。

noun

1. the infliction of extremely painful punishment or suffering

   Synonym:    crucifixion

2. a state of acute pain

   Synonym:    agonysuffering