Objective: To investigate the relationship of phosphonoformate ( PFA) and apoptotic protease-activating factor-1 ( APAF-1) gene and explain the molecular biological mechanisms of PFA in antivirus functions. 目的:了解膦甲酸钠(PFA)与细胞凋亡蛋白酶激活因子-1(APAF-1)基因启动子的关系,为PFA的作用机制提供理论依据。