Effect of α-Tocopheryl Succinate on IAPs Expression in Human Breast Cancer Cells α-生育酚琥珀酸酯对乳腺癌细胞中IAPs家族蛋白表达的影响
Survivin, a member of the inhibitors of apoptosis protein family, correlates with inhibition of apoptosis, proliferation, angiogenesis and multiple drugs resistance. 存活素(survivin)是凋亡抑制蛋白(inhibitorsofapoptosisprotein,IAPs)家族的成员,与凋亡抑制、肿瘤细胞增殖、血管形成及耐药正相关。
In according to recent researches, this article summarized the action of caspase family in apoptosis, the structure characteristics of IAP family, anti-apoptosis principle of IAP family and its negative control. 本文结合近年来的研究进展,综述了Caspase在凋亡中的作用、IAP家族蛋白分子的结构特征、抗凋亡作用机制以及IAPs抗凋亡作用的负调控。
Conclusion: Though IAPS ( International Affective Picture System) is highly internationally-accessible, there are still significant differences between the two sources. The native Chinese Affective Picture System is necessary. 结论:国际情绪图片系统(IAPS)具有较好的国际通用性,但仍由于文化、个性等因素存在差异,因此编制本土化的中国情绪图片系统是有必要的。
Inhibitor of apoptosis protein and strategy of tumor therapy 细胞凋亡抑制蛋白(IAPs)与肿瘤治疗的策略
Recent research has proved: IAPs not only play important roles in regulating cell apoptosis, but also widely participate in the process of mitosis, ubiquitin-proteasome pathway, MAPK mitogen-activated protein kinase and NF-κ B signaling pathways. 最近的研究已经被证实:IAPs不仅与细胞凋亡的规则有关,还在细胞分裂中起非常重要的作用,泛素蛋白水解途径,MAPK促分裂原活化蛋白激酶和NF-κB信号途径[11]。
In recent years, We are very concerned about the inhibiting apoptosis of the apoptosis inhibitor proteins in the world. 近年来关于凋亡抑制蛋白(Inhibitorofapoptosisproteins,IAPs)在抑制凋亡中的作用备受关注。
Rice varieties with different spike LSC elements of the cultivars had significant differences, indicating that IAPS, APD, and there are genetic differences in leaf area. 不同穗型水稻品种叶源量组成因素在品种间存在极显著差异,表明IAPS、APD及叶面积存在着遗传差异。