Conclusion Our results suggested that the influence of pemphigus autoantibody on desmosomes appears at a relative later stage, but the damage of desmosomes is a pivotal step to acantholysis. 结论天疱疮抗体对桥粒及其成分的影响是在较晚期开始的,但桥粒的破坏是棘层松解的关键一环。
A quantity study of acantholysis caused by pemphigus antibody 天疱疮抗体致棘刺松解量化研究
Conclusion The anti PAb antibodies can reduce or block the acantholysis effectively. 结论抗天疱疮抗体与天疱疮抗体结合后能有效地减轻或阻断棘层松解的发生。
Experimental study on the block of acantholysis by anti pemphigus antibody in vitro 抗天疱疮抗体阻断棘层松解的实验研究
Histopathology shows acantholysis with lichenoid dermatitis or keratinocyte necrosis. 组织病理学显示棘层松解、苔藓样皮炎或角质形成细胞坏死。
Furthermore, CTM was also added into the cultured skin organ model of pemphigus in vitro to observing its effect on the inhibition of acantholysis by hydro cortisone ( HC). 将按无毒限量稀释的天疱疮Ⅰ号与HC同时加入此模型中,观察天疱疮Ⅰ号有无抑制棘层细胞松解的作用。
The Role of IL-2, IFN-γ and IL-10 in Pemphigus Acantholysis 白介素2、干扰素γ、白介素10对天疱疮棘层松解影响的研究
Objective To study the blocking effect of anti pemphigus antibodies on acantholysis for finding a new way to treat pemphigus. 目的研究抗天疱疮抗体对天疱疮抗体致棘层松解的阻断作用,探讨天疱疮治疗的新途径。
It is characterized by intra-epidermal acantholysis. 本病的一个显著的特征是表皮细胞间的连结松弛,即表皮发生棘层松解。
Some studies have indicated that some cytokines such as tumor necrosis factor-α ( TNF-α) are important in the process of acantholysis. 近年来的研究表明,肿瘤坏死因子-α(TNF-α)等细胞因子在天疱疮发病的棘层松解过程中也起重要作用。