Method Okabe's acetous cauterization was used to establish the gastric ulcer model in rat anterior gastric wall. The model rats were given drugs respectively for 10 days and then the contents of NO 、 NOS and ET in peripheral tissues of gastric ulcer were detected. 方法采用Okabe氏乙酸烧灼法在大鼠胃前壁造成溃疡模型分别连续给药治疗10d后,定量检测溃疡周围组织NO、NOS以及ET的含量。