Inhibition of Sinomenium Acutum Extract on Monoamine Transmitters Reuptake Objective To study the effects of Sinomenium acutum on monoamine transmitters reuptake by their transporters. 青风藤对单胺类转运蛋白再摄取功能的抑制目的提取分离青风藤不同极性部位,研究它们对单胺类神经递质转运蛋白再摄取功能的影响。
Therefore, the systematical study on the in vivo metabolic changes and rules of the alkaloids of S. acutum would not only provide the pharmacokinetic information for its clinical use, but form the substance basis for further investigation of bioactive constituents of S. acutum in vivo. 因此,系统地研究青风藤中生物碱类成分的体内代谢,不仅可为青风藤的临床用药提供体内药物代谢信息,而且还可为青风藤体内药效物质的阐明奠定基础。
Conclusion The extract of Sinomenium acutum can inhibit the acute rejection of heart transplantation, decrease the level of IL-2 and increase IL-10 in serum of receptor. 结论青风藤醇提取物有抗心脏移植急性排斥作用;可降低受体外周血IL-2水平,升高IL-10水平。