Objective: To investigate the absorption characteristics of aesculin in different intestinal segments of rats. 目的:探讨秦皮甲素在大鼠各肠段的吸收动力学特征。
Method: The study was performed by intestinal perfusion model in rats to observe the effect of absorption sites and concentrations on absorption kinetics of aesculin. 方法:以大鼠在体肠灌流模型从吸收部位、药物浓度考察秦皮甲素的肠吸收动力学情况。
The reactions of aesculin and aesculetin ( two effective components in Chinese medicine) with serum albumin ( BSA and HSA) were investigated by means of fluorescence. 用荧光光谱法研究了中药有效成分秦皮甲素、秦皮乙素与牛血清白蛋白(BSA)、人血清白蛋白(HSA)的相互作用。
Under the optimum conditions, the hydrolysis rate constants of aesculin hydrolysis at five different reaction temperatures were obtained respectively. 在最佳电泳条件下,测定了秦皮甲素在五个不同温度下水解反应的速率常数,并计算了该反应的活化能。
A simple and fast excitation-emission matrix fluorometry coupled with alternating trilinear decomposition algorithm has been developed for simultaneous determination of aesculin and aesculetin in powdered cortex fraxini. 用三维荧光分析结合交替三线性分解算法对秦皮中药成分进行定性定量分析,为直接测定秦皮甲素和秦皮乙素提供了一种快速简洁的方法。
With the contents of aesculin and aesculetin as the technical specifications, three microwave-assisted extraction ( MAE) procedures were studied. 以秦皮甲素和秦皮乙素的含量为指标,研究了3种微波萃取秦皮的方法。
Based on the fluorescence properties of Fraxin and Aesculin, a new thin-layer fluorescence scanning method was proposed for their analysis, and its feasibility was tested by a HPLC method. 建立了薄层荧光扫描法测定秦皮中秦皮苷和秦皮甲素含量的新方法,并用高效液相色谱/紫外检测法进行了验证。
The pharmacodynamic test results indicated that Aesculin has strongly lowering uric acid effect and no damage of renal function, aesculin is more significantly safety than allopurinol in the treatment of hyperuricemia. 药效学研究表明秦皮甲素具有显著的降尿酸作用,对小鼠肾功能无影响,其用药安全性显著高于别嘌醇。
Influence of environment conditions on fluorescence spectra of Aesculin and Aesculetin were investigated. 考察了环境因素对秦皮甲素和秦皮乙素荧光光谱的影响。
Compared with the control group, the BUN of model group, high, medium and low dose aesculin group was no statistical significance. 模型组、秦皮甲素高、中、低剂量组与空白组相比,BUN差异均无显著性。
Various factors influencing the cloud point and phase ratio of the surfactants were evaluated. In the meantime, the transformation of aesculin to aesculetin in Cortex Fraxini extracts was investigated. 对影响表面活性剂溶液浊点和相比的各种因素进行了研究。同时在对秦皮的研究中发现了秦皮甲素和秦皮乙素的转化现象,对其转化的影响因素进行了初步探讨。