Although chiral amino-alcohol ligands have been successfully applied to various kinds of catalytic asymmetric reactions, few examples of the synthesis of chiral multi-dentate ligands, such as tri-or tetra-dentate from amino acids, and their application to asymmetric reactions have been reported. 手性氨基醇衍生物,虽然已经成功地用于多种不对称催化反应中,但是以氨基酸为原料的手性多齿配体的合成和应用研究文献报道较少。