Study on Mitochondrial Damage Effect of Ampelopsin Sodium in Tumor Cells in Vitro 蛇葡萄素钠体外损伤肿瘤细胞线粒体的作用研究
Study on the Selective Cytotoxic Activity of Ampelopsin Sodium on Cancer Cells and Its Mechanisms They work in different ways. 蛇葡萄素钠对肿瘤细胞的选择性杀伤作用及其机理研究这两种抗生素的杀菌机制完全不同。
Effects and Mechanisms of Ampelopsin Sodium on Blood Pressure and Hemodynamics in Rats 蛇葡萄素钠对大鼠血压和血流动力学的影响及其机制研究
Determination of ampelopsin in teng cha extract by first derivative ratio fluorescence spectrometry Studies on Stability in Biological Medium and Preclinical Pharmacokinetic of Ampelopsin Sodium 比值-导数荧光法测定藤茶中的蛇葡萄素蛇葡萄素钠在生物介质中稳定性及临床前药代动力学研究
The Long-term Toxicity of Ampelopsin Sodium by Continuous Intravenous Adminstration in Rats 蛇葡萄素钠连续静脉内给药对大鼠的长期毒性
Study on Anti-tumor Effects and Stability of Ampelopsin Sodium 蛇葡萄素钠抗肿瘤活性及稳定性研究葡萄球菌产生的毒素
Studies on Stability in Biological Medium and Preclinical Pharmacokinetic of Ampelopsin Sodium 蛇葡萄素钠在生物介质中稳定性及临床前药代动力学研究
RESULTS Ampelopsin has stronger antibacterial activity than that of berberine hydrochloride. 结果蛇葡萄素对实验菌株有较好的抑菌作用,其抑菌作用较盐酸黄连素相当或略强。
Objective: To study the chemotaxis effect of ampelopsin with different concentration on monocytes and neutrophilic granulocytes. 目的:观察蛇葡萄素在一定浓度下对中性粒细胞和单核细胞的趋化作用。
Methods: Using a serologic pharmacological method, the inhibitory effects of different dose of ampelopsin on B16 melanoma cells were evaluated by a MTT assay and a flow cytometry. 方法:以血清药理学方法考察不同剂量的蛇葡萄素含药血清对B16黑色素瘤细胞的抑制作用,分别用MTT法及流式细胞术进行评价。
Effect of Ampelopsin on the Blood Sugar of Diabetes Rabbit and Influence of Ampelopsin on NO/ NOS 蛇葡萄素对糖尿病兔的降血糖作用及对NO/NOS的影响
Inhibitory Effects of Ampelopsin on Angiogenesis Inhibition 蛇葡萄素的血管生成抑制作用
Study on Inhibitory Effect of Ampelopsin on Melanoma by Serologic Pharmacological Method 血清药理学方法研究蛇葡萄素抗B16黑色素瘤的作用
Effect of Ampelopsin on the Contraction of Isolated Uterus of Rabbits Induced by Some Mediators 蛇葡萄素对家兔离体子宫平滑肌收缩性能的影响
Conclusion: Ampelopsin possibly acts on melanoma B16 cells by original form drug at the period with a peak of the drug concentration, and inhibits the DNA synthesis of B16 cells. 结论:蛇葡萄素在血药浓度达峰期对小鼠黑色素瘤B16细胞的抑制可能以原型物形式起作用,抑制细胞的DNA合成。
Anti-Tumor Effects of Ampelopsin on Human Lung Cancer GLC-82 Implanted in Nude Mice 蛇葡萄素对人肺癌GLC-82裸鼠移植瘤的抑制作用
BACKGROUND& OBJECTIVE: The authors had firstly reported that ampelopsin possess anticancer effects on several human cancer cell lines in vitro and on transplant mouse B16 melanoma in vivo. 背景与目的:我们先前的研究发现蛇葡萄素在体外对几种人肿瘤细胞以及在体内对小鼠移植性B16黑色素瘤具有抑制作用。
Objective: To observe the antagonism of Ampelopsin ( AP) on the contraction of isolated uterus of rabbits induced by some mediators. 目的:探讨蛇葡萄素(Ampeloptin,AP)对多种物质诱导的子宫平滑肌收缩的抑制作用。