The Effect of Glibenclamide on the K~+-ATP Channels of Pancreatic β TC3 with the Pretreatment of Amylin 胰淀素对优降糖作用于胰岛βTC3细胞ATP敏感性钾通道的影响
The turbulence of excretion of amylin induces insulin resistance. 人体内胰淀素分泌的紊乱是诱导胰岛素抵抗发生的原因之一。
Selection and preliminary identification of human Fab fragement antibody against amylin from phage antibody library The turbulence of excretion of amylin induces insulin resistance. 胰淀素Fab抗体的筛选及初步鉴定人体内胰淀素分泌的紊乱是诱导胰岛素抵抗发生的原因之一。
Amylin was mainly distributed in the expanded mesangial area, Kimmelstiel – Wilson nodules, Bowman's capsule, and in blood vessels. 胰淀素主要分布在肾小球系膜基质增多而扩张的系膜区、K-W结节内、肾小球囊和血管上。
Objective To study the effect and mechanism of amylin upon oral sulfonylurea drugs and its action to stimulate the islet cell secretion of insulin in rats. 目的研究胰淀素对磺脲类降糖药刺激大鼠胰岛细胞分泌胰岛素作用的影响和机制。
Methods pancreatic islet cells from neonatal rats were cultured in vitro, the activity of which was determined by MTT assay after incubation with amylin at different concentrations for varied period of time. 方法应用体外单层培养新生乳鼠胰岛细胞,采用噻唑蓝法测定在不同浓度胰淀素作用不同时间后细胞的活力变化。
Effect of amylin on the formation of reactive oxygen species in islet cells in vitro 胰淀素对离体大鼠胰岛细胞内活性氧生成的影响
The mechanisms of amylin inducing islet β-cell apoptosis 胰淀素引起胰岛β细胞凋亡的机制
Amylin effects on insulin-stimulated glucose uptake of human adipocytes 胰淀素对胰岛素刺激的人脂肪细胞糖摄取的影响
Amylin could enhance glycogenolysis by activating glycogen phosphorylase and thus influence glycogen metabolism. 上述结果提示,amylin可以通过激活糖原磷酸化酶活力,加强小鼠肝细胞的糖原分解过程,促进肝细胞对葡萄糖的释放,从而对肝细胞内糖原储量及糖代谢平衡进行调节。
Effect of amylin on pancreatic islet cells: a preliminary study 胰淀素对胰岛细胞损伤作用的初步研究
Effect of amylin on insulin secretion in rat pancreatic islets and its mechanism 胰淀素对大鼠胰岛素分泌的影响及其机理的探讨
Amylin induces apoptosis of cultured human mesangial cells 胰淀素诱导人肾小球系膜细胞凋亡
Conclusion Amylin acts to directly damage islet cells through decreasing the viability and proliferation of the cells, and the degree of the damage was positively correlated to the concentration and treatment time of amylin. 结论胰淀素对胰岛细胞有直接损伤作用,这种损伤程度与胰淀素浓度及作用时间呈正相关。
Study progress of amylin 胰淀素研究进展
Studies of Mechanisms of Amylin on Insulin Release from Rat Pancreatic β Cells and Sulfonylureas Secondary Failure 胰淀素对大鼠胰岛β细胞分泌胰岛素及磺脲类药物继发失效机制的研究
Amylin can inhibit insulin releasing, increase the plasma level of free fat acid ( FFA). 胰淀素能抑制胰岛素的释放,提高血浆游离脂肪酸的水平。
Forecast Methods of Macromolecular Amylin and Amylum Caused Beer Haze A Big Cheater 大分子糊精和淀粉导致啤酒混浊的预测方法
Conclusion Amylin plays a directly inhibiting role in glucagon secretion. 结论胰淀素对胰高血糖素的分泌有直接抑制作用;
Effect of amylin on blood glucose and lipid metabolism in rats 胰淀素对大鼠葡萄糖和脂肪代谢的影响
Conclusion: Amylin can induce apoptosis of human mesangial cells in vitro. 结论:amylin对人系膜细胞具有细胞毒性作用,并可诱导系膜细胞的凋亡。
Conclusion Amylin level of severe PIH patients increases. There was no correlation between amylin and PIH. 结论重度PIH患者血胰淀素水平增高,胰淀素与PIH发病无明显的相关性。
Association study of serum amylin level and body composition in simple obese patients 单纯性肥胖患者血清胰淀素水平与体成分的相关性研究
Results: Seventy-two ( 48.3%) of patients have positive staining of amylin in the renal tissue. Amylin was found mainly in the expanded mesangial area, segmental sclerosis, K-W nodules, the Bowman's capsule as well as in blood vessel. 结果72例DN患者(48.3%)肾组织Amylin染色阳性,Amylin主要沉积在肾小球系膜基质增多而扩张的系膜区、K-W结节内、增厚的球囊壁和病变的血管壁。
High content of macromolecular amylin and amylum was the main reason for beer hazes in its later stage. 高含量大分子糊精和淀粉是引起啤酒后期浑浊的主要原因。
As a kind of pleiotropic hormone, amylin plays multiple roles in the substance and energy metabolism in our body. 现己发现它是一个多效激素,以多重角色参与了机体的物质及能量代谢过程。