Results: The ischemic contracture, cubitus varus and anchylosis did not occurred in all the patients followed more than 2 years. 结果:本组获2年以上的随访,且无缺血性肌挛缩、肘内翻和关节僵硬等并发症。
PI3K/ Akt signaling pathway was activated in Pten-deficient articular chondrocytes. The Pten knockout mice gradually exhibit humpback, faltering steps and anchylosis as they grew up. Pten敲除小鼠的关节软骨细胞中PI3K/Akt信号通路持续激活,成年的Pten敲除小鼠逐步表现出驼背、步履蹒跚、关节僵硬等OA大体表现。