aneuploidy

1. Detection of Aneuploidy from Single Cells by Array-Comparative Genetic Hybridization A Combined Method Applied to the Classification of Microarray Gene Expression Data
   SNP基因芯片结合多重置换扩增技术检测单细胞非整倍体的研究混合法用于基因芯片数据的分类分析
2. Analysis for Application of the Fluorescent in Situ Hybridization on the Prenatal Diagnosis of Chromosome Aneuploidy in the Uncultured Amniocytes
   荧光原位杂交在未培养羊水细胞产前诊断中的临床应用研究
3. Although a low-level of aneuploidy, an abnormal number of chromosomes, may contribute to neuronal diversity, high levels of aneuploidy may result in developmental abnormalities and disease.
   虽然染色体数目异常（少量非整倍体）可能对神经细胞多样性有好处，但是大量的非整倍体会导致进行性的异常及疾病。
4. Chromosomal instability leads to a condition known as aneuploidy, in which chunks of DNA are either missing or duplicated.
   染色体的不稳定就会导致非整倍体的发生，这样DNA的记忆单位就会丢失或重复。
5. Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.
   该药物能够准确的将正确的染色体数目导入每一新细胞，产生非整倍体细胞，能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。
6. Aneuploidy The condition, resulting from nondisjunction of homologous chromosomes at meiosis, in which one or more chromosomes are missing from or added to the normal somatic chromosome number.
   在减数分裂的过程中同源染色体不分离而造成的一条或多条染色体的缺失或增加。
7. Abnormal chromosome numbers ( aneuploidy) and structural chromosomal aberrations are invariably found in the cells of malignant tumors.
   染色体数目异常（非整倍体）和染色体结构畸变经常可见于恶性瘤细胞。
8. To find out, researchers in the Cleveland lab created and analyzed mouse models with cells having a highly variable number of chromosomes to discover if such aneuploidy made the mice more tumor-prone.
   Cleveland教授实验室的研究者建立染色体数目有明显变异的小鼠模型，并分析该非整倍体小鼠模型是否更容易罹患肿瘤。
9. BSR: What first got you interested in looking at the possibility that aneuploidy might cause cancer?
   什么原因促使你注意到非整倍体可能是癌症的原因？
10. By analyzing the chromosome constitute of meiosis stage, the incidences of aneuploidy was no significant difference in the various medium.
    对第二减数分裂期的卵子染色体构成进行了分析，异数体卵子的出现率在各种培养基中无明显差异。
11. The worse the neoplasm, the greater the degree of aneuploidy and the worse the prognosis.
    肿瘤越恶性，异倍性程度越大，报告结果就越差。
12. And, notes Hughes, finding aneuploidy in one or two cells of an embryo does not always mean that the embryo will not be viable.
    而且如Hughes指出的，从一个胚胎中发现1到2个非整倍性的细胞并不意味着胚胎就无法存活。
13. But the more unexpected feature of their findings was discovered when the research team added other genetic errors to mice with a high rate of aneuploidy tumor development was slowed.
    但是，在让小鼠具备其他基因缺陷时他们发现意外特性，即高比例的非整倍体肿瘤的形成速度放慢。
14. One of the purposes of the FASTER trial was to calculate the contemporary procedure-related loss rate after midtrimester amniocentesis using patients who were recruited for aneuploidy screening.
    病人们被募集来参加非整数倍的筛选，FASTER测验的目的之一是预测当代妊娠中期羊膜穿刺术相关的流产率。
15. Methods The DNA aneuploidy style was studied in73 patients with thyroid lesions using image cytometry and the specimen was acquired by fine-needle aspiration.
    方法对73例甲状腺肿瘤和结节性甲状腺肿患者以细针穿刺涂片，用图像细胞仪进行分析。
16. Aneuploidy is a chromosomal imbalance of one or a few chromosomes above or below the normal human chromosomal number of46, which may lead a child to have abnormalities including Down Syndrome.
    非整倍性是指个体的染色体不均衡或者或者某些染色体比正常人的染色体数目多或者少包括唐氏综合症。
17. Aneuploidy is associated with cancer.
    非整倍体与肿瘤相关。
18. Objective To study the correlation between the histological grading and DNA aneuploidy.
    目的探讨DNA含量与乳腺浸润性导管癌组织学分级的关系。
19. Objective: To investigate the correlation between maternal age and oocyte chromosome aneuploidy abnormality.
    目的：直接从卵细胞水平研究女性年龄与其卵细胞染色体非整倍体间的相关关系。
20. To study the relationship between the embryo morphologic indicators and the chromosome 21 aneuploidy;
    利用荧光原位杂交技术对发育迟缓和胚胎碎片多的胚胎进行21号染色体分析，探讨21号染色体非整倍性与胚胎形态学指征的相关性；
21. Conclusion Both nondisjunction, balanced and unbalanced predivision of chromatids are involved in the oocyte aneuploidy formation.
    结论同源染色体不分离和姐妹染色单体平衡性及非平衡性过早分离这三种机制均参与了卵细胞非整倍体的产生。
22. Conclusion: Oocyte aneuploidy could be an important reason of repeated IVF failure.
    结论：卵细胞的非整倍体异常可能是导致反复lVF-ET失败的一个重要原因。
23. Unlike other sex chromosome aneuploidy, there are no general characteristic physical features for triple X patients.
    与其他性染色体非整倍体不同，XXX核型的患者并没有显著的身体特征。
24. DNA aneuploidy is one of the characteristics of malignant tumors.
    DNA非整倍体是恶性肿瘤的特征性标志之一。
25. Conclusion DNA aneuploidy, SPF and EGFR is associated with malignant degree of gliomas.
    结论：DNA异倍体的发生、SPF值、EGFR阳性率与胶质瘤恶性级别正相关。
26. DNA index and aneuploidy may be regards as an important reference in prescribing chemotherapy regiments for acute leukemia.
    DNA指数和DNA非整倍体率可作为制定急性白血病患者化疗方案时的重要参考指标。
27. Results The difference of DNA aneuploidy style between benign and malignant tumor cells was significant.
    结果甲状腺恶性肿瘤细胞与良性肿瘤细胞DNA倍体类型有非常显著的差异。

noun

1. an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)