Objective To study the cause, mechanism and clinical features of cerebral angiospasm, and provide help for the diagnosis and treatment of cerebrovascular spasm. 目的探讨脑血管痉挛的病因、机制及临床特点,为脑血管痉挛的正确诊治提供方法。
After Fasudil was marketed in Japan in 1999, it has been used for treating cerebral ischemia, cerebral angiospasm, angina pectoris. 法舒地尔于1999年在日本上市后,临床上用于治疗脑缺血及脑血管痉挛,它对稳定型心绞痛病人有抗心绞痛作用。
The principal mechanism of microcirculation disturbance include: damage and engorgement in vascular endothelial cells, angiospasm in micrangium, neutrophils adherence and aggregation resulting in obstruction of vas capillare lumens. 产生微循环障碍的主要机制包括:毛细血管内皮细胞损伤肿胀、微血管痉挛、中性粒细胞黏附聚集堵塞管腔等。