Anti-HAV seroconversion rate reached more than 80.00% 1~ 2 months after inoculation. 免后1~2个月的抗-HAV阳转率均达80%以上。
The result showed that after modulating the sensitivity the anti-HAV IgM diagnostic kit was fully acceptable to be used for HAV-Ag detection. 经过调控灵敏度后,抗HAVIgM诊断试剂盒完全可以用来检测HAV-Ag。
The results showed that the anti-HAV positive seroconversion rate was 100% in all children, the GMT was 3,013mIU/ ml. 结果显示:所有加强免疫的儿童抗HAV阳转率为1000%,几何平均滴度(GMT)为3013mIU/ml;
The local and systemic reactions were observed within 3 days after injection. Both anti-HAV and ALT were detected at wk 0,2,3,4,6,8 and liver puncture was performed at wk 0,4,8 for histopathological examination. Autopsy was down at the end of observation. 接种3d内,每天观察有无局部和全身反应,0,2,3,4,6,8周采血测ALT及甲肝抗体,0,4,8周肝穿做组织病理检查,观察到期尸检。
Methods ELISA and MEIA methods were used to detect total anti-HAV antibody, and compare their sensitivity and accordance. 方法用ELISA和MEIA法检测血清甲肝总抗体,再进行两种方法的互相比较。
A r-capture ELISA for detecting IgG antibody to Hepatitis A virus ( HAV) has been developed and compared with contest ELISA of anti-HAV. It is useful that anti-HAV IgG negative sera inhibit nonspecific reaction in the capture ELISA of anti-HAV IgG. 用抗甲型肝炎病毒(HAV)IgG阴性血清处理以抑制非特异反应,提高灵敏性的捕获法酶联免疫吸附试验检测甲型肝炎病毒特异IgG抗体,并与竞争法检测总抗HAV进行了比较。
Rapid construction of recombinant baculovirus carrying anti-HAV Fab gene using a baculovirus shuttle vector 利用穿梭质粒快速构建含抗HAVFab基因的重组杆状病毒
Anti-HAV IgG positive rate of 761 persons was 81.21%. 761名健康人群抗-HAvIgG阳性率81.21%。
Conclusions Clinical symptom, disease history, age and the level of RF are useful for the judgment of anti-HAV IgM positive. 结论抗HAV-IgM阳性的确定应依据临床症状、病史、年龄及RF水平来综合判定以降低假阳性。
In the population without the vaccination, anti-HAV IgG positive rate increased with age. The positive rate of the population above 20 years old almost exceeded 90%. 在无甲肝疫苗接种史的人群中,抗-HAvIgG阳性率随年龄而上升,20岁以上人群的阳性率几乎都在90%以上。
A series of IgM, IgA and total anti-HAV levels were measured in 60 patients with hepatitis A from 1 or 2 weeks to 1 year after onset. They were divided into two groups according to clinical course of the disease. 对60例甲型肝炎患者血清抗甲型肝炎病毒(HAV)IgM、IgA及总抗体从发病起进行了1年动态观测,并以病程、病情不同分组观察分析。
Methods: 310 sera of healthy children ( 0-24 months old) were collected. Total anti-HAV antibody were assayed by ELISA, then the antibody level were compared and analyzed among different months groups. 方法:采集310名0~24月龄健康儿童血清,测定抗HAV总抗体,分析不同月龄组的抗体水平。
Virus marking substance. Result: anti-HAV IgM, anti-HCV. anti-HDV& non-HEV IgM all negative. Two patients 'HBsAg were positive. 采患者血清做甲、乙、丙、丁、戊型肝炎病毒标志物检测,结果:43名患者的抗-HAVIgM,抗-HCV,抗-HDVIgM,抗-HEVIgM全部阴性,HBsAg阳性2例。
Application of Anti-HAV IgM Diagnostic Kit in Detecting HAV-Ag 甲肝IgM抗体诊断试剂盒在甲肝病毒抗原检测中的应用
Methods The serum levels of RF were determined by transmission turbidimetry and that of anti-HAV IgM with ELISA. 方法RF采用透射比浊法测定,抗HAV-IgM采用酶联免疫法检测。
Objective To understand anti-HAV level of children at age of 1~ 7 years old and estimate the effect of domestic HAV attenuated vaccine immunization. 目的了解本市1~7岁儿童甲肝抗体水平,评价国产甲肝减毒活疫苗的接种效果。
Dynamic Changes of Serum IgM, IgA and Total Anti-HAV Levels in Patients with Hepatitis A 甲型肝炎患者血清特异性IgM、IgA及总抗体动态变化与临床意义
Objective To obtain the anti-HAV antibodies. 目的获得人源性甲型肝炎病毒(HAV)抗体。
Results The serum levels of RF were significantly higher in the test group. There was linear regression relation between RF and OD of anti-HAV IgM. 结果实验组RF明显增高,且与抗HAV-IgM检测的光密度OD值之间存在直线回归关系。
Detection with Capture ELISA of Anti-HAV IgG and Comparision with Contest ELISA of Anti-HAV 用ELISA捕获法测抗甲型肝炎病毒IgG及与竞争法测抗甲型肝炎病毒的比较
Tbe seroconversion rate of anti-HAV was 100% at second week after first inoculation. The valence of antibody was 374.8-937mIU/ml at 4th week. 首次注射后2周100%抗体阳转,4周效价为3748mIU/ml~937mIU/ml。