CONCLUSION The combination antiallergenic therapy is useful for treating patients with acute hepatitis B, and type I allergenic reaction may play a role in the pathogenesis of acute hepatitis B. [结论]联合抗过敏疗法对急性乙型肝炎疗效显著,从而间接证明了免疫球蛋白E及其介导的Ⅰ型变态反应在急性乙型肝炎发病机理中的致病作用。