Marine polyunsaturated fatty acids have good bioactivity in the aspect of antimalarial, antimycobacterial, antifungal, and so on. 海洋多不饱和脂肪酸在抗疟、抗结核、抗真菌等方面具有良好的生物活性。
Tanshinones: antimycobacterial agents& its bile excretion and biotransformation in rat liver 抗分枝杆菌活性成分&丹参酮的胆汁排泄与肝内转化
Objective To study antimycobacterial activities in vitro of the compounds that target Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein ( ACP) synthase ⅲ( FabH), and to obtain a novel, effective, and safe antituberculous agent. 目的研究结核分枝杆菌脂肪酸合成酶FabH为靶标的化合物的体外抗结核活性,研制新的高效、安全的抗结核药物。