STUDIES ON THE BETA-LACTAM ANTIBIOTICS STRUCTURE-ACTIVITY RELATIONSHIP& ⅱ. Hydrophilic reactivity and structure-activity relationship in penicillins β-内酰胺类抗生素构效关系的研究&Ⅱ.青霉素类抗生素的亲水性和构效关系
Head spore Sai Fu sodium molecular structure stabilizes, not being destroyed by beta-lactam enzyme, can not produce resistance to drugs or the resistance to drugs alternating therefore. 头孢噻呋钠分子结构稳定,不被β-内酰胺酶破坏,因此不会产生抗药性或交叉抗药性。
Methods: 133 case reports of ADR associated with beta-lactam antibiotics were collected and analysed by Chongqing ADR Monitoring Center. 方法:对重庆市ADR监测中心收到的β-内酰胺类抗菌药物ADR病例报告进行分析。
Coli to imipenem was the lowest, about 2.6%, however, it was above 30.0% towards the most beta-lactam antibiotics; 大肠埃希菌对亚胺培南耐药率最低为2.6%,而对大部分β-内酰胺类药物的耐药率>30.0%;
Beta-lactam antibiotic have broad-spectrum and strong antimicrobial activity but have the stability to DHP-I. this paper introduce its development and principle of antibiosis. β-内酰胺类抗生素具有抗菌谱广、抗菌活性高、对肾脱氢肽酶-I稳定的特点,介绍了β-内酰胺类抗生素的发展状况及其抗菌活性并对其抗菌原理进行了理论阐述。
Study on resistant genes of beta-lactam antibiotics from clinical isolates of Pseudomonas aeruginosa 绿脓假单胞菌β内酰胺类耐药基因研究
Development in pharmacokinetics/ pharmacodynamics research of beta-lactam antibiotics β-内酰胺类抗生素的药动学/药效学研究进展
Bioconversion of beta-lactam antibiotics and the application of biotechnological approach β-内酰胺抗生素生物转化与生物工程技术的应用
The isolation and characterization of beta-lactam supersensitive microorganism β-内酰胺抗生素类超敏感菌的分离与特性