brucine

1. Determination of Entrapment Efficiency and Drug Loading of Brucine Solid Lipid Nanoparticles Lyophilized Powder by HPLC
   HPLC法测定马钱子碱固脂纳米粒冻干粉的包封率和载药量
2. Objective: To establish a method for the determination of brucine and strychnine in BingChan cream by RP-HPLC.
   目的：建立冰蟾乳膏中马钱子碱和士的宁的含量测定方法。
3. Experimental Study of Brucine on Breast Cancer Bone Metastasis in Mice
   马钱子碱对裸鼠乳腺癌骨转移的实验研究
4. Determination of the Plasma Protein Binding Rate of Plasma Brucine in Rats by HPLC
   高效液相色谱法测定大鼠血浆中马钱子碱与血浆蛋白的结合率
5. Objective To establish the analytical method of strychnine and brucine in Gukang tablet by TLC.
   目的建立骨康片中士的宁和马钱子碱的含量测定方法。
6. Objective: To investigate the analgesic effect of brucine by transdermal administration.
   目的：考察马钱子碱经皮给药的镇痛作用。
7. Comparison study of the anticancer effect between Brucine and Brucine liposome in mice with transplanted tumor in Vivo
   马钱子碱及其脂质体对移植性荷瘤小鼠的抗肿瘤作用的对比研究
8. AIM: To compare brucine with the mixed solution of brucine and nano-liposomes to observe analgesic and anti-inflammatory effects of the brucine nano-liposome for local use on skin were studied.
   目的：考察纳米马钱子碱脂质体局部外用的镇痛及抗炎效果，并同马钱子碱、马钱子碱和纳米脂质体的机械混合溶液进行了比较。
9. Study on Pharmacokinetics of brucine in mice
   口服马钱子碱后小鼠体内的药动学研究
10. Comparison of Brucine and Nitrogen Oxides Isobrucine in Their Anti-cancer and Anti-oxidation Effect
    马钱子碱与异马钱子碱氮氧化物抗肿瘤细胞生长及抗氧化损伤作用的比较
11. OBJECTIVE: To find a method which can analysis strychnine and brucine in semen strychni using 722 or 721 type spectrophotometer.
    目的：探索一种用可见分光光度计分析马钱子中士的宁和马钱子碱的方法。
12. The high and middle dosage of Semen strychni 、 Brucine could promote DNA and proteoglycan synthesis of chondrocyte apparently.
    对软骨细胞DNA、蛋白多糖、胶原合成的影响：马钱子、马钱子碱高中剂量组有明显促进兔软骨细胞DNA合成及分泌蛋白多糖的作用，且有一定的量效关系。
13. To study the effects of brucine on cardiac electrophysiology, using a standard microelectrode technique, recording the action potentials ( AP) and contractile force ( Fc) simultaneously.
    研究马钱子碱对心肌电生理方面的影响。采用常规微电极技术同步记录收缩力的方法，观察了马钱子碱对豚鼠心脏乳头肌动作电位（Ap）及收缩力（Fc）的影响。
14. Effect of brucine on the action potentials in guinea pig papillary muscles
    马钱子碱对豚鼠心脏乳头肌动作电位的影响
15. CONCLUSION: Liposome is an effective carrier for the local use on skin of brucine.
    结论：纳米脂质体化可以显著提高皮肤外用马钱子碱的镇痛和抗炎效果，是马钱子碱皮肤局部外用制剂的良好载体。
16. Conclusion: Brucine can effectively promote the proliferation of chondrocyte.
    结论：马钱子碱能有效促进软骨细胞增殖。
17. Conclusion This method can be used to detect brucine and strychnine in liver.
    结论该方法可望用于生物材料中的马钱子碱和士的宁的检测。
18. Conclusion Compound brucine has remarkable analgesic effect with power potency and long duration.
    结论复方马钱子碱腹腔注射有明显的镇痛作用，且起效迅速，作用强而持久。
19. AIM: To study the tissue distribution of brucine in mice.
    目的：研究马钱子碱在小鼠体内的组织分布。
20. To establish a method for the determination of brucine and strychnine contents in Tongbiling Tablet.
    建立测定通痹灵片中马钱子碱、士的宁含量的方法。
21. In vitro Transdermal Penetration of Brucine Liposomes in Excised Rats Skin and Irritation to Rabbits Skin
    马钱子碱脂质体的大鼠离体透皮性能和兔皮肤刺激性研究
22. The results showed that this CE-MS method accords with criterion of bioanalysis. 3. To investigate pharmacokinetic properties of strychnine and brucine in rats.
    结果表明方法符合生物分析的要求。3.应用CE-TOF/MS，对马钱子碱和士的宁在大鼠体内的药物动力学性质和组织分布情况进行研究。
23. It was validated that the selectivity, linear range, recovery of extraction. matrix effect, stability, precision and accuracy of the method met the requirements. It can be used for pharmacokinetics research of brucine and strychnine. 3.
    结果表明，方法的专属性、线性范围、提取回收率、基质效应、稳定性、精密度和准确度均符合生物样品测定要求，该方法可以用于马钱子碱和士的宁的药代动力学研究。
24. Objective: Brucine, a main component of nux vomica, is one of indole alkaloids.
    目的：马钱子碱（Brucine）为吲哚型生物碱，是马钱子的主要有效成份之一。
25. Its influence on brain concentration is greater than blood. The result shows that brucine may has more significant effects on transporters. 3.
    马钱子碱具一定的自身诱导作用，对脑内浓度的影响大于血药浓度，说明其对转运蛋白的影响可能更显著。
26. High performance liquid chromatography ( HPLC) methods for determining brucine and strychnine were established. The microstructures of all samples were examined by scanning electronic microscope ( SEM).
    建立了马钱子碱、士的宁的高效液相色谱（HPLC）含量测试方法，测定马钱子粉中马钱子碱、士的宁含量并对各组样品的微观形貌进行了扫描电镜（SEM）分析。
27. The contents of strychnine and brucine and the methodology should be determined by HPLC to control the toxical components. Meanwhile comparative study of strychnine and brucine contents from different processed products was performed.
    为了控制毒性成分的含量，本研究采用HPLC法对士的宁碱和马钱子碱进行含量测定，并进行方法学考察，同时对马钱子不同炮制品所制成品中士的宁碱和马钱子碱含量进行比较研究。
28. The main active components are strychnine and brucine.
    搜风丸含有大毒药材马钱子，其主要成分为士的宁碱和马钱子碱。
29. A lot of researches showed that strychnine and brucine have a wide of pharmacological activities, but they also have considerable toxic. Strychnine and brucine belong to the drugs of narrow therapeutic window, litter change on the concentration may cause the poison.
    大量的研究表明，马钱子碱和士的宁具有广泛的药理作用，但是它们也具有相当大的毒性，均属于治疗浓度窗很窄的药物，浓度的稍微改变便可能引起药效的改变甚至中毒。
30. An LC-MS/ MS method was developed and validated for the determination of brucine and strychnine in rat plasma and tissues. Samples were extracted by mixed solvent.
    建立大鼠血浆样品和组织样品中马钱子碱和士的宁的LC-MS/MS测定方法，以溶剂萃取法处理样品，并对方法进行了确证。

noun

1. a bitter alkaloid poison resembling strychnine and extracted from nux vomica