Objectives To explore the diagnostic value of cytological brushings and bile tumor markers determination during ERCP for cholangiocarcinoma. 目的探讨ERCP及细胞刷检和胆汁肿瘤标志物测定在胆管癌诊断中的价值。
Result Aneuploidy, mainly featured in gains of chromosomes 7,8 and 12 and loss of chromosome 9 were observed in all of the 7 cases with cells from endobronchial brushings diagnosed as or suspicious of cancer cells by cytology. 结果在细胞诊断为癌或可疑癌细胞的7例中均发现染色体异倍体,主要特征为7、8和12号染色体增多及9号染色体丢失;
Method Cells gained from endobronchial brushings of 14 patients with lung cancer were examined by FISH with chromosomes 7,8,9 and 12 specific centromere probes. 方法选取7、8、9和12号染色体特异着丝粒探针,用FISH技术检测14例肺癌患者支气管镜刷取细胞中上述染色体异倍体。