An Experimental Study on Cerulenin Induced Apoptosis of Human Osteosarcoma Cells 浅蓝菌素阻遏骨肉瘤细胞增殖及诱导凋亡的实验研究
Study on preparation of cerulenin liposomes and its effects on proliferation of tumor cells in vitro 浅蓝菌素脂质体的制备及其对肿瘤细胞体外增殖影响的研究
AIM: To investigate the effect of fatty acid synthase inhibitor-cerulenin on the growth and apoptosis of human gastric cancer cells. 目的:研究脂肪酸合成酶(FAS)抑制剂cerulenin对人胃癌细胞株增生的影响及诱导凋亡的作用。
The fatty acid synthesis of the oral mucosa tissues was only mildly affected by cerulenin. 口腔粘膜在变蓝菌素处理后脂肪酸合成活性略下降,至4h时仅下降20%;
[ Conclusions] The cerulenin can remarkably improve the immune function of wistar rat. [结论]浅蓝菌素可明显改善机体的免疫机能。
Objective To observe the effects fatty synthase ( FAS) inhibitor on the growth and metabolism of wistar rat and to investigate the mechanism of cerulenin on diet and body weight control. 目的观察脂肪酸合成酶抑制剂浅蓝菌素对wistar大鼠生长及代谢的影响,探讨浅蓝菌素控制饮食与体重的作用机制。