Methods: The fresh removed specimen from 12 normal cervixes, 18 cervical intraepithelial neoplasia ( CIN), and 34 cervical cancers ( CC) were collected and the mutation of DNA polymerase β gene were detected by RT-PcR, PCR-SSCP, and sequencing analysis. 方法:采用RT-PCR法、PCR-SSCP分析法对12例正常宫颈组织、18例宫颈上皮内瘤样病变(CIN)及34例宫颈鳞癌组织进行polβ突变检测。