The effect of cryptotanshinone on the expression of ICAM-1 in TNF-α-induced human umbilical vein endothelial cells 隐丹参酮对TNF-α诱导的人脐静脉内皮细胞粘附分子ICAM-1表达的作用
Objective To investigate the antiangiogenesis effect of cryptotanshinone on chick embryo chorioallantoic membrane ( CAM). 鸡胚尿囊膜(CAM)是研究体内血管发生的重要模型之一。
Studies on the Effect of Cryptotanshinone on Insulin Resistant Ovarial Granular Cells by DNA Microarray 基因芯片研究隐丹参酮对胰岛素抵抗卵巢颗粒细胞基因表达的影响
Electron Spray Ionization Mass Spectrometry ( ESI-MS) and Electron Ionization Mass Spectrometry ( EI-MS) were used to elucidate the structure and fragmentation pathway of Cryptotanshinone ( CT). 采用电喷雾电离质谱(ESI-MS)和电子轰击质谱(EI-MS)两种质谱技术,对隐丹参酮的结构和裂解途径分别进行了研究。
To use the method of ultrasonic extraction to extract the fat-soluble components in radix salviae miltiorrhizae, the determination of cryptotanshinone, tanshinone I and tanshinone ⅱ A by RP-HPLC. 用超声法提取丹参饮片中的脂溶性有效成分,然后用反相高效液相色谱法同时测定丹参饮片中隐丹参酮、丹参酮Ⅰ和丹参酮ⅡA的含量。
Study on the Room Temperature Phosphorescence of Cryptotanshinone and Tanshinone IIA 隐丹参酮和丹参酮IIA滤纸基质室温磷光法的研究
And the permeability significantly increased when cryptotanshinone was perfused with P-glycoprotein inhibitor verapamil. 加入P-糖蛋白抑制剂维拉帕米后其通透率增高。
Effects of Cryptotanshinone and Tanshinone Α on Proliferation, Lipid Synthesis and Expression of Androgen Receptor mRNA in Human Sebocytes in vitro 丹参酮对人皮脂腺细胞增殖、脂质合成及雄性激素受体mRNA表达的影响
Conclusions The method is sensitive, rapid and accurate for the measurement of cryptotanshinone content in β-cyclic dextrin tanshinone ear drops. 结论该方法操作简便,测定结果准确可靠,可用于β环糊精丹参酮滴耳液中隐丹参酮含量测定。
Study on the Fluorescence Properties of Cryptotanshinone and Tanshinone ⅱ A and Their Analytical Methods 两种丹参酮化合物分子的荧光特性及分析方法的研究
RESULTS: Release of tanshinone ⅱ A agrees with Higuchi equation while cryptotanshinone performs a significant first burst effect in the very first day. 结果:其中丹参酮A的释放符合Higuchi方程,而隐丹参酮则在第一天有突释现象。
The fat-soluble ingredients are extracted from it by ethyl alcohol, in which mainly are Cryptotanshinone, Tanshinone ⅰ and Tanshinone ⅱ A. 丹参浸膏是丹参经乙醇提取的脂溶性成分,主要有隐丹参酮、丹参酮Ⅰ和丹参酮ⅡA三种。
Room temperature phosphorescence of cryptotanshinone and tanshinone IIA has been studied in detail. 考察了隐丹参酮和丹参酮IIA的滤纸基质室温磷光法(PS-RTP)特性。
Preparation of cryptotanshinone solid dispersion and its properties 隐丹参酮固体分散体的制备及性质研究
Methods Caco-2 cell monolayer model was used to investigate the bi-directional transport of cryptotanshinone. The effect of time, drug concentration and inhibitors on the absorption of cryptotanshinone was studied. 方法用Caco-2细胞单层模型研究隐丹参酮的双向转运,并考察时间、药物浓度及抑制剂对隐丹参酮吸收的影响。
Objective To develop a quantitative method for determination of cryptotanshinone content in β-cyclic dextrin tanshinone ear drops. 目的建立高效液相色谱测定β环糊精丹参酮滴耳液中隐丹参酮含量的方法。
Objective To establish a sensitive HPLC method with UV detection for the determination of tanshinone ⅱ_A ( TS ⅱ_A) and cryptotanshinone ( CT) in rat plasma and to study pharmacokinetics of Radix Salviae Miltiorrhizae ( RSM) liposoluble components in rat in vivo. 目的建立大鼠血浆中丹参酮ⅡA和隐丹参酮的HPLC-UV检测法,并研究丹参脂溶性成分在大鼠体内的药动学。
Experimental study on the absorption mechanism of cryptotanshinone single-pass intestinal perfusion model 隐丹参酮在小肠吸收机制的实验研究
Analysis of Cryptotanshinone by Electron Spray Ionization Mass Spectrometry and Electron Ionization Mass Spectrometry 隐丹参酮的电子电离和电喷雾电离质谱分析
Aim To observe the protective effects of tanshinones ( tanshinone IIA, tanshinone I, cryptotanshinone and dihydrotanshinone) against liver injury in mice loaded with restraint stress. 目的研究4种丹参酮类化合物对拘束应激引起小鼠肝损伤的保护作用。
Cryptotanshinone and Dihydrotanshinone had significant cytotoxicity and radiosensitization effects on cervical cancer Hela cell. In addition, the capacity of delaying tumor growth in nude mice transplanted with hepatoma cell was evaluated. 隐丹参酮和二氢丹参酮对宫颈癌Hela细胞均有较好的细胞毒性和放射增敏作用,对肝癌移植的荷瘤小鼠,具有抑制和延迟肿瘤生长的作用。