HPLC Determination of Cucurbitacin B in Radix Trichosanthis HPLC测定天花粉中葫芦素B的含量
Objective To study the distribution of cucurbitacin B loaded PLGA nanospheres in mice. 目的研究葫芦素B聚乳酸-羟基乙酸毫微球小鼠体内分布。
Effect of cucurbitacin B on the expression of VEGF and oxidative stress in the liver fibrosis tissue due to Schistosoma japonicum infection 葫芦素B对小鼠日本血吸虫肝纤维化组织VEGF及氧化应激的影响
Combined Inhibitory Effect of Cucurbitacin B and Gemcitabine in Pancreatic Cancer 葫芦素B与吉西他滨联合应用对胰腺癌的抑制作用及其机理研究
Effect of concentration, pH and solvent on photolysis rate of cucurbitacin E solution 浓度、pH值及溶剂对葫芦素E溶液光解速率的影响
In vitro transdermal permeability of cucurbitacin B hydro-alcohol gels 葫芦素B水-醇凝胶的体外经皮通透性
In vitro and in vivo inhibitory effect of cucurbitacin B on the growth of breast cancer cells 葫芦素B在体内外对乳腺癌细胞的生长抑制作用
Preparation and Optimization of Formulation of PLGA Microspheres Containing Chinese Herbal Extract Cucurbitacin B 中药提取物葫芦素B-PLGA微球的制备及处方工艺优化
Effects of Cucurbitacin BE Polylactic Acid Nanoparticles on Human Oral Squamous Carcinoma Cell Lines 人口腔鳞癌细胞系对淋巴靶向葫芦素BE聚乳酸纳米微粒的敏感性研究
Cucurbitacin B sc 0.1mg/kg or 0.2mg/kg obviously inhibited the expression of Fas and FasL, and number of apoptotic cells in dose-dependent manner. sc葫芦素B0.1mg/kg和02mg/kg可使Fas和FasL的表达明显降低并呈剂量依赖性。
Factors that influence the formation of cucurbitacin lipid emulsion 葫芦素脂肪乳剂成型性影响因素考察
Absorption, distribution, and excretion of [~ 3h]-cucurbitacin B in animals [~3H]-葫芦素B在动物体内的吸收、分布、排泄
Conclusion: Cucurbitacin B has the protective effects on the liver injury induced by CCL 4. 结论:葫芦素B对CCL4所造成的肝损伤有一定的保护作用。
Effect of Cucurbitacin Bon expression of Fas and FasL in hepatocyte in rats 葫芦素B对大鼠肝内Fas及FasL表达的抑制作用
The preparation of~ 3h-cucurbitacin B ~3H-葫芦素B的制备
Chemosensitivity study of human oral squamous cell cancer cell lines to cucurbitacin BE 口腔鳞癌细胞系对葫芦素BE的敏感性研究
But this mechanism was not cleared yet. The aim of our work is to study cucurbitacin B protecting effects on hepatocytes associated with inhibiting apoptosis signals transduction. 但是其作用机制还不是很清晰,本实验探讨的是葫芦素B是否通过抑制凋亡信号转导而达到保肝的目的。
Microbial transformation with the E. coli, yeast and molds to cucurbitacin B-2-O-glucoside were transformed, the results show that cucurbitacin B content is not changed. 微生物转化用了大肠杆菌,酵母菌以及霉菌对葫芦素B-2-O-葡萄糖苷进行转化,结果显示葫芦素B含量也没有改变。
The accumulation of cucurbitacin C in fruits will result in bitterness in cucumber and seriously affect the quality of cucumber. 果实中积累葫芦素C会导致黄瓜苦味,严重影响黄瓜品质。
Final choice of the acid hydrolysis method, a low concentration of acetic acid and hydrochloric acid to its hydrolysis, the content of cucurbitacin B has increased. 最后选择酸水解的方法,用低浓度的醋酸和盐酸对其水解,葫芦素B的含量有所提高。
However, the effects of Cucurbitacin E on tumor angiogenesis and its potential molecular mechanism are still unknown. 但是,CuE对肿瘤血管新生的作用及其潜在的分子机制尚无报道。
Furthermore, we found that Cucurbitacin E remarkably induced HUVECs apoptosis, inhibited tumor angiogenesis, and suppressed human prostate tumor growth in xenograft tumor model. 我们发现CuE显著诱导内皮细胞的凋亡,在荷瘤模型中通过抑制血管新生抑制肿瘤的生长。