epigenetic

美 [ˌɛpədʒəˈnɛtɪk]

adj.  后成的;外遗传的;后生的;渐成的

医学

COCA.37207



双语例句

  1. This meeting will focus on genetic, epigenetic and biochemical mechanisms underlying the pathogenesis of diabetes.
    这次会议将集中在遗传,表观遗传和生化机制上的糖尿病发病机制。
  2. Recent studies have highlighted the differential expression between male and female genomes, the mechanism of epigenetic processes and the regulation network of development.
    新近的研究集中在雌雄基因组的差异表达、后生过程的控制机理和发育调控网络等方面。
  3. These so called epigenetic modifications persist through cell cycle.
    这些所谓的表观修饰存留遍及细胞周期。
  4. This gene regulation is accomplished by epigenetic processes that control gene expression without altering DNA.
    这是基因调控是由控制基因的表观遗传完成的,并没有改变DNA。
  5. The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
    组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰,在基因的表观遗传转录调控中起着关键的作用。
  6. Cancers arise through the accumulation of genetic mutations and epigenetic modifications.
    癌症是通过基因突变和后生修改的积累产生的。
  7. Gene function may be altered by either a change in the sequence of the DNA or a change in epigenetic programming of a gene in the absence of a sequence change.
    基因功能可能通过DNA在序列上的一个变化或通过缺乏序列变化的一个基因在表观编程中的一个变化而被改变。
  8. Here we've established a new role for SUMOylation, mediating the interaction between protein and protein methylation in epigenetic regulation.
    在这里我们已经建立了SUMO结合的新角色,在表观遗传调控中调控的蛋白质和蛋白质甲基化。
  9. In the last year, several new findings about epigenetic modifications of gene expression were reported in different arthritides.
    过去的一年里,关于基因表达的表观修饰的一些新发现在不同的关节炎性皮疹中被报道。
  10. Therapeutically, it may mean that preventing oxidative stress may stop epigenetic changes in DNA.
    在治疗学上它意味着预防氧化应激可以中止DNA的表观遗传学改变。
  11. Plants use these epigenetic silencing mechanisms extensively to control development and parent-of-origin imprinted gene expression.
    植物广泛地使用这些表观沉默机制来控制发育及亲本来源的印记基因表达。
  12. DNA methylation, amongst the known epigenetic modi? cations, appears to play a crucial role in leukaemogenesis.
    在已知的表观遗传修饰中,DNA甲基化似乎在白血病形成中起到一个重要的作用。
  13. Epigenetic variation plays an important role in plant growth and development, including DNA methylation, histone modification, chromosome remodeling, and RNA interference and so on.
    表观遗传变异对于植物的生长发育起着重要作用,主要包括DNA甲基化、组蛋白修饰、染色体重塑和RNA干涉等。
  14. Advancement of Epigenetic Modifications Regulate Influences Transgenic and the early Development of Cloned Embryo
    表观遗传修饰对转基因和克隆胚早期发育的影响研究进展
  15. A similar question remains for the inheritance of the epigenetic characteristics from parents to offspring.
    表观遗传特性的同样问题存在于亲代和子代之间。
  16. Aberrant DNA methylation is one of the major characteristics of tumor cells in addition to genetic and other epigenetic alterations.
    DNA甲基化的异常是肿瘤细胞的主要特征之一,此外还有遗传的和其他表观上的改变。
  17. One of the best known epigenetic factors is DNA methylation, which is a major mechanism for regulation of gene expression.
    表观因子中最著名的一个是DNA甲基化,它是基因表达调控的一个主要机制。
  18. Ongoing studies have identified biochemical and nuclear mechanisms, genetic determinants, epigenetic factors and non-coding RNAs in the pathogenesis of diabetic complications.
    正在进行的研究已经确定了生化和核机制,遗传因素,表观遗传因素在糖尿病并发症的发病机制中的非编码RNA。
  19. Its association with HCF-1 suggests an epigenetic mechanism of gene repression in pluripotent cells.
    而在多能干细胞中磺胺吡啶与HCF-1的结合也表明了一种基因阻遏的表观遗传机制。
  20. Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease.
    DNA中胞嘧啶碱基的甲基化在很多真核细胞中提供了一层表观控制,它对于正常生物学和疾病有着重要的意义。
  21. Epigenetic modifications plays an important role in gene expression and the early development of cloned embryo.
    表观遗传修饰在基因表达和克隆胚的早期发育方面有重要作用。
  22. Recent studies showed that wide hybridization is often accompanied by an array of genetic and epigenetic changes.
    近年来的研究表明远源杂交的过程常常伴随大量的基因组变异和表观遗传变异发生。
  23. As a epigenetic mark for the centromeric chromatin, CENP-A is a histone H3-like protein specific to centromeres.
    CENP-A作为着丝粒染色质的表观遗传学标记,是染色质核心组蛋白H3在着丝粒上的特异变体。
  24. Gene silencing is a kind of epigenetic phenomenon discovered in transgenic plants in recent years.
    基因沉默是近几年来在转基因植物中发现的一种后生遗传现象。
  25. Biologists have suspected for years that some kind of epigenetic inheritance occurs at the cellular level.
    生物学家很多年来一直怀疑一些表观遗传发生在细胞水平上。
  26. Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
    靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
  27. We are eager to explore the underlying transcriptional and epigenetic mechanisms of somatic cell reprogramming.
    我们将研究在体细胞重编程过程中的转录调控和表观遗传调控机制。
  28. These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.
    这些修饰调控组蛋白-DNA相互作用,为核小体迁移的表观遗传调控添加了新的维度。
  29. With epigenetic drugs, it is possible to reverse aberrant gene expression profiles associated with different disease states.
    用表观药物,可能逆转与不同疾病状态相关的异常的基因表达谱。
  30. Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene expression.
    已知表观遗传过程,例如DNA甲基化调控组织特异基因表达。