C/ T ( T/ C) and A/ G ( G/ A) transitions were the major types of single base mutation. 其中以C/T(T/C)转换和A/G(G/A)转换为主要的单碱基突变类型。
There was interaction between polymorphism of TNF-α gene promoter and exposure time in the occurrence of silicosis. The risk of silicosis in those with G/ A+ A/ A genotype was significantly higher than G/ G genotype in low accumulative exposure. TNF-α基因-308位点基因多态性在矽肺发病过程中与接尘工龄存在交互作用,当累积接尘量较低时,G/A+A/A基因型携带者发生矽肺的危险性较G/G基因型明显增加。
The G/ A polymorphisms in intron 27 of fibrillin-1 gene in 101 Chinese Hans who were studying and working in University of Tsukuba, Japan were analyzed with PCR-ASO method. 采用PCR&ASO方法,对日本筑波大学101名中国汉族留学人员的DNA样品进行了原纤维蛋白-1基因(FBN1)第27内含子G/A多态性测定。
Results showed that the plasma fibrinogen level in the samples of genotype A/ A and G/ A was higher than that in the samples of G/ G in the same group ( P0.001). 结果表明,两组携带A等位基因者(基因型为G/A和A/A)血浆Fg水平均较同组G/G基因型者明显增高(P0.001);
[ Results] There were significant differences of GG, GA, AA genotypes and G/ A alleles frequencies between patients with Type 2 diabetes and nondiabetic subjects ( P < 0.01). 结果T2DM组GG、GA、AA基因型及G/A等位基因频率与非T2DM组比较有显著统计学差异(P<0.01);
Study on G/ A Polymorphisms in Intron 27 of Fibrillin-1 Gene in Chinese Han Population 中国汉族人群原纤维蛋白-1基因(FBN1)第27内含子G/A多态性
The value of TNF-α at the position-308 ( G/ C) and ( G/ A) and the corresponding radiographic stage of sacro-iliac joint damage was assessed to investigate the influence of gene polymorphisms on AS. 以X射线骶髂关节片分级和肿瘤坏死因子α-308位点(G/C)和(G/A)的对应值评估其对疾病程度的影响。
Conclusion ( 1) The polymorphism at the site of G/ A might be associated with PD, but there might be no genetic association of polymorphism at this site with ET. 结论(1)G/A位点多态与PD的发病有关联,G/A位点多态与ET无关。
For TNF α-238G/ A site, three genotypes ( G/ A, G/ G and A/ A) were detectable; 肿瘤坏死因子α-238G/A位点可检测到的基因型有G/A、G/G和A/A3型;
Two alleles of the COMT gene as a result of a G/ A transition in the exon 4 can lead to different COMT enzymatic activities. COMT是儿茶酚-O-甲基转移酶的编码基因,其第4外显子的一个G/A转换可产生不同活性的等位基因。
Glucokinase gene promoter G/ A variant is associated with higher fasting glucose levels 葡萄糖激酶基因启动子G/A变异与空腹高血糖相关
A method of identifying the individual agent in modeling the MAS based on the G/ A matrix 基于G/A矩阵的MAS建模中个体Agent的识别方法
Objective To study the association of beta-fibrinogen ( Fg) gene-148 C/ T and 448 G/ A polymorphisms, plasma Fg concentration, molecular reactivity and the type of cerebral infarction. 目的研究纤维蛋白原(fibrinogen,Fg)浓度、分子聚合功能及FgBβ-148、448基因多态性与脑梗塞类型的关系。
The relationship between donor TNF α-308 ( G/ A) genotype and recipient acute GVHD in allo-BMT 异基因骨髓移植中供者TNFα-308(G/A)基因型与受者急性移植物抗宿主病的关系
The genotype of site SNP43 ( G/ A) and SNP44 ( T/ C) in Calpain 10 gene was detected by Polymerase chain reaction and Allele specific amplification ( PCR-ASA). 应用聚合酶链式反应双引物等位基因特异性扩增法(PCR-ASA)检测Calpain10基因SNP43位点(G/A)及SNP44位点(T/C)基因型。
Lung cancer risk associated with genetic polymorphism in myeloperoxidase (-463 G/ A) in a Chinese population 髓过氧化物酶基因-463G/A多态与中国人肺癌遗传易感性