Irritation action of rats stimulated by haemostat inhibited and the energy metabolism of mice decreased after ip Ge total alkaloids. Ge total alkaloids also could assist the hypnotic effect of a hypnotic subthreshold dose of chloral hydrate in mice. 钩吻总碱能抑制大白鼠由止血钳刺激所致的激怒反应,降低小白鼠机体的能量代谢,并且能协同闽下剂量的水合氯醛对小白鼠的催眠作用。