BACKGROUND: Fms-like tyrosine kinase-3 ( FLT3) gene is one of the receptors for growth factors in early hematogenesis. 背景:Flt3基因是近年来发现的早期造血生长因子受体基因。
Results Neutrophil G score and the percent of pelger abnormality of MDS were significantly variant than that in normal control ( P < 0 001), and also significantly correlated with abnormal hematogenesis. 结果显示:MDS组外周血中性粒细胞颗粒积分(G-score),Pelger畸形所占百分率(PPP)与正常对照组相比差异显著(P<0.001)。MDS组PB、BM的G-score、PPP有显著相关性。
Conclusion If we mastered morphological features about blood cells and morbid hematogenesis 'cells, applied clinical analysis and did morphological examination of bone marrow cells with care, the differential diagnosis was easy to assess between MDS with reduced erythrocyte series and PRCA. 结论:只要牢固掌握血液细胞形态学特征及病态造血细胞形态学特征,认真细致的临床分析和骨髓细胞形态学的动态观察,是能够对二者进行鉴别诊断。
Conclusion: The Stasis eliminating and Kidney tonifying Decoction can facilitate the hematopoietic microenvironment recovery, decrease the level of hematopoietic negative regulatory factors, thus facilitate the hematogenesis recovery in aplastic anemia mice. 结论:化瘀补肾汤能促进再障小鼠骨髓微环境的修复,减少造血负调控因子的释放,从而促进造血功能恢复。
Dysfunction of hematogenesis is a main complication under the condition of chemotherapy, radiotherapy, unexpected leakage of radioactive material and nuclear warfare. 造血功能障碍是恶性肿瘤化学药物治疗和大剂量放射线治疗、放射源意外泄漏和核战争条件下急性放射损伤的主要并发症之一。