Construction and expression of heptad repeat region of canine distemper virus fusion protein 犬瘟热病毒融合蛋白七肽重复区基因的克隆表达
Subclone, Expression, Purification and Its Structure Analysis of Heptad Repeat Regions from the F Protein of Newcastle Disease Virus 新城疫病毒F蛋白七肽重复序列区的亚克隆、表达、纯化及结构分析
Objective To identify the effects of heptad repeat regions ( HR1 and HR2) of fusion protein ( F) on the specific membrane fusion of paramyxoviruses. 目的了解副粘病毒融合蛋白(F)分子上的七肽重复序列(HR1、HR2)在特异性膜融合中的作用。
Mutations in a Hydrophobic Heptad Repeat Region of the Core Protein inhibited Capsid Assembly of The Human Hepatitis B-Like Virus 人类乙型肝炎样病毒核心蛋白中第7位疏水性氨基酸重复肚段区域的突变可以抑制病毒核衣壳的组装
The research results of Retrovirus, Filovirus, Orthomyxovirus and Paramyxovirus showed that 6-helix bundle formed by heptad repeat regions of fusion proteins was the key to start membrane fusion. 对反转录病毒、纤丝病毒、正粘病毒和副粘病毒等的研究表明,其囊膜表面融合蛋白的七肽重复区HR1和HR2相互作用形成六螺旋束是引发膜融合的关键。
Like other enveloped viruses, Mumps virus ( MuV) fusion protein ( F) may possess two heptad repeat domains ( HR). 腮腺炎病毒(MuV)同其他囊膜病毒相似,在融合蛋白(F)中具有两个七肽重复序列结构域(HR)。
Fusion protein of Paramyxovirus consists of fusion peptide ( FP) and heptad repeat 3 ( HR3), both of which contribute to membrane fusion. 此外,副粘病毒膜融合过程中,融合蛋白的融合肽(FP)、HR3等区域被证明与融合蛋白的构象变化有关。