histones
英
美
网络 组蛋白; 组蛋白抗体; 组织蛋白; 组蛋白类; 组蛋白质
双语例句
- These enzymes activate genes by attaching chemicals called acetyl groups to histones, the spool-like proteins that hold DNA in a tightly wound form.
这些酶通过粘附于所谓的化学剂乙酰组蛋白来激活基因，像线圈一样的蛋白以紧密创伤形式缠绕着DNA。 - Histones are a group of proteins that are associated with chromosomes.
组蛋白是一类结合在染色体上的蛋白质。 - Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.
其他的工作集中在组蛋白乙酰化，这种化学修饰可以使DNA从组蛋白缠绕中解离出来，产生基因活性。 - With histones, methylation is well recognized as a regulatory mechanism, but the fact that other proteins are also be modified in the same way is a relatively new observation.
甲基化作为一个调控组蛋白的机制现在已经研究的比较透彻，但其它的蛋白也有同样的调控机制却很少见。 - Instead, epigenetic processes attach chemical groups to genes or to histones, proteins that are intertwined with DNA to form chromosomes, to activate genes or to shut them down.
相反，表观遗传过程主要是将化学结合到基团或组蛋白，后者是与DNA交织在一起形成染色体，从而激活或关闭基因。 - Epigenetic marks, such as the modifications of the histones, are also important for the specialisation of the body's cells.
表观遗传标记，例如组蛋白修饰，对于机体细胞的分化也很重要。 - In plants and animals, gene expression can be altered by changes not to DNA itself but rather chemical modifications either to DNA or to histones that interact with DNA.
在植物和动物中，基因表达能够通过非DNA自身，而是通过与DNA相互作用的DNA或组蛋白的化学修饰的变化来改变基因表达。 - Past structural studies of methylation were hindered by the extreme difficulty of constructing homogeneous samples of histones bearing methyl groups attached to specific lysine residues.
过去甲基化的结构研究被阻碍的原因是因为很难制备组蛋白特定部位赖氨酸甲基化的均一样品。 - Histones make up the spool of proteins around which DNA winds so that it is packaged compactly in the nucleus.
组蛋白组成蛋白线轴，DNA缠绕在它的周围，使DNA紧密地包装在细胞核中。 - In a second set of analyses, co-author Jeffrey Hansen and Xu Lu measured how methylation affected the condensation of recombinant chromatin formed from the methylated histones.
在第二轮的分析中，共同作者JeffreyHansen和XuLu测量了这种甲基化的组蛋白形成的重组染色质中，甲基化怎样影响它的凝聚。 - The function of plant genomes depends on chromatin marks such as the methylation of DNA and the post-translational modification of histones.
植物基因组的功能依赖于染色质标记，诸如DNA的甲基化和组蛋白的转录后修饰。 - For example, they found that proteins called histones, which help control a gene's activity, were being altered.
他们发现一种有助于控制基因活性的组蛋白的改变。 - Histones are protein-found in eukaryotic cell nuclei, tightly bound to DNA, which has many phosphate groups.
组蛋白是存在于真核细胞核中的与含很多磷酸基团的DNA紧密结合的蛋白质。 - Luger and her colleagues next packaged the modified histones they received from Shokat's group into recombinant nucleosomes and chromatin.
Luger和他的同事随即包装了从Shokat小组得来的修饰过的组蛋白，形成核小体和染色质的重组体。 - Matthew Simon, a postdoctoral fellow in Shokat's laboratory, produced pure samples of H3 and H4 histones with the desired methylation marks.
MatthewSimon是Shokat实验室的博士后，他制作出了携带期望甲基标记的H3和H4组蛋白纯样品。 - With this methyl-group mimic in hand, his team could then synthesize purified histones with methyl groups inserted at any desired point on the histone structure.
利用这种甲基基团的仿制品，他的小组可以合成任何一点携带甲基基团的纯组蛋白。 - Histones are basic proteins.
组蛋白是碱性蛋白。 - The reactivity of histones with some MAbs reveals the possible pathogenesis of anti-histones antibody production in autoimmune diseases.
组蛋白与某些单克隆抗体发生的交叉反应性揭示了在自身免疫性疾病中抗组蛋白自身抗体产生的可能致病原因。 - These results suggest that an accumulation of highly acetylated histones is due to inhibition of histone deacetylation by butyrate.
冷追击实验的结果提示，丁酸钠引起高乙酰化组蛋白的积蓄，确是通过其对组蛋白脱乙酰基过程的抑制作用而实现的。 - Studies on many aspects show that there are four main reasons which cause the epigenetic effects; the methylation of DNA, the acetylation of histones, the change of chromatin structure and the alteration of protein configuration.
多方面的研究表明，导致后生效应的可能原因主要有四个方面：DNA的甲基化、组蛋白的乙酰化、染色质结构背景的改变和蛋白质构型的变化。 - The Raman spectroscopic study of complexation and isolation of DNA and histones in chromatin
染色质的DNA与组蛋白复合和分离的拉曼光谱研究 - High resolution NMR studies of nucleic acids and histones
核酸和组蛋白的高分辨核磁共振研究 - And DNA molecules binds to histones and non-histone proteins to form chromatin to engage in this process.
在细胞中，DNA分子与组蛋白及非组蛋白结合形成可进行反复组装与去组装的染色质分子参与这一过程。 - Covalent modifications, such as acetylation occur in the N-terminal amino acids of histones.
在真核生物中，组蛋白是染色质基本结构一核小体中的重要组成部分，其N末端氨基酸残基可发生乙酰化等共价修饰。 - This architecture of chromatin is strongly influenced by posttranslational modifications of the histones.
染色质的结构受组蛋白翻译后修饰的影响。 - In eukaryotic cells, DNA is packaged with histones in the form of chromatin.
在真核细胞中，DNA与组蛋白包装形成染色质。 - Chromatin modification consists of covalent modifications of the N-terminal tails of the nucleosomal histones and DNA cytosine methylation.
染色质修饰包括核小体组蛋白N末端的共价修饰和DNA的胞嘧啶甲基化。 - In addition to histones, several other cellular proteins including transcription factors and tumor suppressor are subject to methylation.
除了组蛋白之外，很多其它的细胞功能蛋白，包括转录因子和抑癌因子等，都被发现可以发生甲基化修饰。 - Acetylation of histones and other nuclear proteins plays an important role in cancer development and progression.
组蛋白和其它核蛋白的乙酰化在肿瘤的发生发展中起着重要作用。