Angiotensin ⅱ stimulates the syntheses of DNA, RNA, protein and collagen in isolated cardiomyocytes and cultured cardiac fibroblasts from hypertrophied rat heart 血管紧张素Ⅱ刺激肥大心肌细胞和心肌成纤维细胞核酸蛋白质及胶原合成
Hypertrophied myocardium is prone to proarrhythmic toxicity and development of the torsade de points type of ventricular tachycardia. 肥厚心肌对于抗心律失常药物的致心律失常毒性非常敏感,容易发生尖端扭转型室速。
The present study was to observe these two factors in the hypertrophied ventricles and aortas of sinoaortic-denervated rats. 本研究观察去窦弓神经大鼠肥厚心室和主动脉组织中这两因子的改变。
In contrast it is characterised with multi-channels and nonspecific disorder in the hypertrophied myocardium in the acquired heart disease. 而后天性心脏病的心肌肥大是多离子通道病变而非特殊性。
But, while banking has become a hypertrophied monster, we still need to understand how the industry got so big in the first place in order to right-size it. 但是,尽管银行业已经成为一头肥厚的怪物,我们还是首先需要了解该行业究竟是如此变得如此庞大,以便将其规模予以最佳合理化。
The low voltage activated current resembles T-type calcium current, suggesting the electrophysiological changes of hypertrophied cardiomyocytes may indicate some transformations such as expressions of fetal genes and regulations of cell growth in hypertrophied left ventricle. 分析表明,这一电流具有类似T型钙通道电流的特征,提示在心肌肥大发生过程中的细胞电生理改变可能反映了胚胎期基因的表达、细胞生长调控等多方面的变化。
To examine changes of collagen network and Matrix Metaloproteinases ( MMPs) activity in hypertrophied rat myocardium. 探讨压力负荷增高性心肌肥厚时心肌胶原网络及心肌细胞外基质金属蛋白酶(MMPs)活性的变化。
Objective To search a simple, safe and effective osteotomy for hypertrophied mandibular angle. 目的探索一种简便,安全,有效的下颌角肥大截骨术。
AIM To study the characteristic of the rapidly activating component ( Ikr) and the slowly activating component ( Iks) of the delayed rectifier K+ current in guinea pig hypertrophied ventricular myocytes induced by thyroxine. 目的在甲状腺素诱导的豚鼠心肌肥厚模型上,研究肥厚心肌细胞延迟整流钾电流(IK)中快激活成份(Ikr)及慢激活成份(Iks)离子通道特征。
Expression of Ang ⅱ receptors in excess load-pressured hypertrophied cardiac muscles of rats 压力负荷性大鼠肥厚心肌中AngⅡ受体的表达
The I Kr and I Ks are reduced in hypertrophied cardiac muscle, which lead to prolongation of action potential duration and provide conditions for early after depolarization and TdP. 心肌肥厚时IKr、IKs的减少导致动作电位时间(APD)延长,为早后除极(EAD)和TdP的产生创造了前提条件。
The Acute and Chronic Effects of Amiodarone on Currents in Isolated Ventricular Myocytes of Hypertrophied Rats 胺碘酮对大鼠肥厚心室肌细胞离子流的急性及慢性作用研究
Results: It was found that the myocardial chymase like activity increased markedly in hypertrophied rat ( 2,6,12 weeks); 结果:术后2、6、12周心肌肥厚组大鼠心肌组织糜酶样活性较同期正常对照组显著增高(P<0.01);
[ Conclusion] Atorvastatin can prevent partly gap junction remodeling of hypertrophied myocardium induced by pressure overload. 结论阿托伐他汀能部分防止压力负荷诱导的心肌肥厚时的Cx43重构。
Effect of atorvastatin on gap junction remodeling in hypertrophied myocardium Propranolol pretreatment protects ischemic hypertrophied myocardium in rat 普萘洛尔预处理对大鼠肥厚心肌缺血再灌注损伤的保护作用及其机制探讨阿托伐他汀对肥厚心肌缝隙连接重构的影响
Study on Ischemia-Reperfusion Injury in the Hypertrophied Myocardium 肥厚心肌缺血再灌注损伤与心脏肾素
Conclusion: ADM is activated as a circulation hormone in thy hypertrophied model. 结论:在此心肌肥厚模型中肾上腺髓质素作为循环激素被活化,可能是一种代偿性升高。
These findings suggest that the protein synthetic activity was increased in the hypertrophied myocardial cells. 本实验动物的心肌细胞,正处在工作负荷增加,蛋白质合成旺盛的心肌细胞肥大代偿期。
Effect of mechanical stretch on connexin 43 gene in SHR hypertrophied ventricular myocyte 机械牵拉对自发性高血压大鼠肥大心室肌细胞连接蛋白43表达的影响
Conclusion Over-expressed endothelin-1 gene may contribute to ventricular remodeling in hypertrophied rats. 结论压力负荷性大鼠表达上调的ET1参与心室重构。
These results suggest that autophagy of cellular elements seems to play an important regulative role in hypertrophied process and dilated T-tubules actually reflect myocardial adaptive changes. 这些结果说明,细胞成份的自体吞噬降解在心肌肥大过程中起着重要调节作用,扩张的T管也反映了心肌细胞外吐加快的适应性改变。
Aim Effects of captopril on angiotensin ⅱ type 1 receptors ( AT1R) and angiotensin ⅱ type 2 receptors ( AT2R) were studied in excess load-pressured hypertrophied cardiac muscles of adult rats. 目的研究卡托普利对压力超负荷性肥厚心肌中血管紧张素Ⅱ1型受体与2型受体表达的影响。
KB-R7943 completely blocked the activating effects induced by E-4031 in both of normal and hypertrophied cardiomyocytes. R7943可完全阻断正常组和肥厚组心肌细胞由E-4031诱导的激动作用。尼卡地平不能阻断E-4031的增加作用。
Inhibition of Na+/ Ca+ exchange induces the suppression in systolic and diastolic function of myocardium, especially in hypertrophied heart. 抑制心肌Na+/ca2+交换将导致心肌收缩和舒张功能降低,这种抑制作用在压力负荷型肥厚心肌表现更为显著。
The Remodeling of Gap junction and Its Influences on Conduction Properties in Hypertrophied Left Ventricle 心肌肥大时间隙连接分布的改变及其对传导特性的影响
Method: bFGF and TGF β 1 gene expression were detected by immunochemistry and in situ hybridization in 32 human hypertrophied heart ( right and left ventricle, each 16). 方法:用免疫组织化学及原位杂交技术检测32例(左、右室心肌各16例)肥大心肌组织中bFGF和TGFβ1的表达。
Effects of glucose metabolism mediated by PDH on apoptosis of hypertrophied cardiac myocytes during post-hypoxia reoxygenation PDH调控的糖代谢途径对缺氧后复氧的大鼠肥大心肌细胞凋亡的影响
[ Objective] To investigate the effect of atorvastatin on gap junction remodeling in hypertrophied myocardium induced by pressure-overload. 目的探讨阿托伐他汀对心肌肥厚时缝隙连接重构的影响。
Kocher demonstrate the transplantation of stem cell can decrease apoptosis of hypertrophied myocytes in the peri-infarct region and improve cardiac function. Kocher等报道移植造血干细胞可改善心肌梗死周边区肥大心肌细胞的凋亡。因此提出干细胞不仅具有分化作用,也可以通过一些途径抑制损伤部位细胞凋亡的发生。
All 20 clones formed hypertrophied lenticels and adventitious roots by Day 6 to 14 of flooding. 20个无性系均在淹水6~14d后形成了膨大皮孔和不定根。