Determination of Nine Sedatives and Hypnotics Illegally Adulterated into Chinese Proprietary Medicine by LC/ MS ( n) Trap LC/MS(n)法对中成药中非法添加9种镇静催眠类化学药品检测方法的研究
Sedatives and hypnotics are widely prescribed to elderly persons with symptoms of depression, anxiety, and sleep disturbance. 镇静与安眠药物被广泛地处方给老年忧郁、焦躁及睡眠障碍的病患。
Certain drugs such as benzodiazepines, which are tranquillisers and hypnotics. 某些药物,如苯二氮类药物,这是镇静剂和安眠药。
In treatment, elderly patients were prescribed more hypnotics and experienced more side effects from psychotropic drugs. Besides, they received more physical treatment outside the psychiatric field. 治疗上,老无病患有更高比率使用安眠药,并合并更多的药物副作用,而且接受更多的其他生理疾病的治疗。
Objective: To evaluate the effectiveness of blood purification treatment on acute toxication of hypnotics and alcohol. 目的:评价血液净化治疗安眠药及酒精急性中毒的疗效。
Objective: To study the influence of sedative hypnotics on autonomic activities and sleep effects in different kinds of mice, and to provide reference of choosing animal for studying medicine influencing neurological function. 目的:观察地西泮和戊巴比妥纳对不同种属小鼠自主活动和睡眠效应的影响,为筛选影响中枢神经系统功能的药物提供可参考的选择动物的依据。
Conclusion: Most suicide cases in emergency department are young people, female, most of them use hypnotics or pesticides. 结论:急诊自杀病例以年轻人、女性居多,采用安眠药、农药为主要手段。
Benzodiazepines are a class of sedatives and hypnotics, and 33 of them are international controlled. 苯并二氮杂卓类药物(Benzodiazepines,BZDs)是具有镇静催眠作用的一类药物。其中33种被列入国际控制药物。
METHODS After having established the mice model of analgesics and hypnotics, we injected the mice with GABA A-receptor antagonist and observed changes of sleep time using awaken test, pain threshold hot-plate test and writhing times writhing test. 方法建立小鼠催眠、镇痛模型后,在小鼠催醒、热板、扭体实验中,分别观察用药后小鼠翻正反射消失持续时间、痛阈或扭体次数的变化。