The origin of non-coding sequences, especially introns, is an outstanding issue that has been receiving continuous debate for the last two decades. 非编码序列,特别是内含子的起源,是一个重要的悬而未决的问题。
By freeing introns from the need to splice themselves, the spliceosome would in effect have encouraged introns to proliferate, mutate and evolve. 剪接体的出现让插入子不再需要自行剪接,结果等于鼓励插入子增生、突变与演化。
We also found that genes that have lost their introns many millions of years ago evolve especially fast near where the introns once resided. 我们还发现,曾经含有但数百万年前已丢失内含子的基因的进化率也是很快的。
Noncoding DNA, containing introns, repetitive elements, and potentially active transposable elements, requires effective mechanisms for its long-term silencing. 非编码DNA,包括内含子,重复元件,和潜在激活转座子,其长期的沉默需要有效的机制。
The introns are cut out by processing enzymes in the nucleus and the exons ( coding sequences) ligated together. 核内的加工酶切下内含子,同时外显子(编码序列)连接在一起。
Because of its two promoters and many different splicing modes of introns, p63 gene encodes many kinds of P63 isoforms. p63的两个不同启动子和多种内含子剪接方式,导致p63基因编码产生多种亚型P63蛋白。
In short, the entry of introns into eukaryotes may have initiated an explosive new round of molecular evolution, based on RNA rather than protein. 简单的说,插入子进入真核生物后,可能启动了新一回合爆炸般的演化,这次的主角是RNA,而非蛋白质。
Instead of being junky molecular relics, introns could have progressively acquired genetic functions mediated by RNA. 插入子非但不是毫无用途的分子遗骸,反而可能以rna为中介,逐步得到遗传上的功能。
For all sequences, information on related genes, exons, introns, gene products and taxonomy is available, as well as selected genome maps and RNA secondary structures. 对于所有的序列,关于相关基因、外显子、内含子、基因产物和分类学,以及挑选的基因组图谱和RNA二级结构信息是可利用的。
Of course, as long as introns needed to splice themselves in and out of genomes, their sequences could not have deviated much from that of group II introns. 当然,只要插入子得靠自己剪接进入或移出基因组,它们的序列就不能与第二类插入子相差太多。
Messenger RNA ( mRNA) does not contain introns, these being removed during the transcription process. 信使RNA中没有内含子,它们在转录后加工的过程中被切除了。
This indicates that this tweaking of the dual role sections of genes is also what evolution does when introns are removed. 这表明,当内含子去掉后,基因里有双重功能片段的连接部分也会发生进化。
SCYA 107 gene consisted of 4 exons and 3 introns. 该基因由四个外显子和三个内含子组成;
The genomic organization is composed of eight exons and seven introns. 基因组由八个外显子和七个内含子组成。
This gene contains four exons and three introns. 此基因含有4个外显子、3个内含子,外显子与内含子接头符合GT-AG法则。
The AMS genomic DNA has complex organization including 7 exons and 6 introns. AMS基因组DNA有一个复杂的结构,包含有7个外显子和6个内含子。
Human GnRH-R gene contains three exons and two introns. 人GnRH-R基因含三个外显子和两个内含子。
The FABP genes consist of 4 exons and 3 introns. 脂肪酸结合蛋白基因都是由4个外显子和3个内含子构成。
Moreover, 2 mutations in introns, 1 in promoter region and 1 SNP were first reported. 发现1个启动子区突变、2个内含子突变和8个SNP位点,其中一个单核苷酸多态性(SNP)位点以往未见报道。
It also gives a new interpretation of the exons, introns and pseudogenes in the program perspective. 还给出了外显子、内含子和假基因在程序视角下的新的解释。
The gene contain two introns and three exons. 该基因含2个内含子,3个外显子。
It contained four exons and three introns. 在softberry上分析,该基因包含有4个外显子和3个内含子。
Genomic sequences analysis revealed the four AGPs genes have no introns. 基因结构分析显示这四个AGPs基因都没有内含子。
All the genes are without introns, and totally identical in the CDs region. 所有基因均没有内含子,尤其是在CDS的起始区和终止区,序列完全相同。