irreversibly

1. ADJ 不可逆转的;不可挽回的;不可撤销的
   If a change is irreversible, things cannot be changed back to the way they were before.
   1. She could suffer irreversible brain damage if she is not treated within seven days...
      如果她在 7 天之内没有得到治疗,她的大脑有可能遭受不可逆转的损伤。
   2. The reforms are irreversible.
      改革没有回头路。

1. Antagonists tend to be small molecules that bind irreversibly to the receptor preventing its normal function, while agonists may be small or large molecules ( e.g. peptide or protein hormones).
   抑制剂一般是小分子，他们不可逆转地结合在受体上阻碍其正常功能，而兴奋剂可以是小或大分子。
2. To get familiar with the basic ideas and techniques, it is best to set up a test environment, because some of the actions could irreversibly damage data if they are performed incorrectly.
   如果您想进一步了解基本的思想与技术，那么您最好创建一个测试环境，因为如果数据没有得到合适的处理的话，那么有些不当的操作将有可能使数据受到不可恢复的毁坏。
3. Unless we act decisively and act now, the situation may deteriorate catastrophically and irreversibly.
   如果我们不采取果断行动，不立即采取行动，形势就可能继续恶化并导致灾难性的后果，造成无法挽回的局面。
4. Men and women may not be fully equal yet, but the rules of the game have been profoundly and irreversibly changed.
   可能男性和女性之间仍然没有达到完全的平等，但游戏规则已彻底改变。
5. Maggie, I'm not worried about you and Cory, or me and Cory, or you being irreversibly screwed up.
   麦琦，我不是担心你和考力或是我和考力或是你错得怎么不可收拾。
6. This old tradition is irreversibly disappearing.
   这种传统习俗永远地消失了。
7. Agriculture in the developing nations is not irreversibly committed, to a particular pattern of intensification.
   发展中国家的农业并没有完全为某种集约化形式所束缚。
8. So suppose we do it irreversibly.
   假设它是不可逆的。
9. Blocks the action of target enzymes by binding nearly irreversibly to their active site.
   与附近目标酶的活性位点不可逆的结合。
10. The habits of at least one generation, and significant parts of others, are now irreversibly changed when it comes to sharing, recommending and locating each other in real time.
    至少整整一代人以及其他群体中很大一部分人的某些习惯现已被不可逆转的改变，人们已经熟悉了分享、推荐以及彼此实时定位。
11. If they go wrong, it may irreversibly alter course of your life, your business, your project, your relation with the customer and so on.
    如果出现错误，将会不可扭转地改变你的生活、你的发展、你的项目、你与客户的关系、等等等等。
12. To cause to lose ( energy, such as heat) irreversibly.
    消耗，使耗散不可逆地失去（能量，如热）
13. The dire predictions of a key report on international oil supplies released Wednesday suggest that oil prices could move irreversibly over the$ 100-a-barrel threshold in the not too distant future, as the global economy faces a serious energy shortage.
    星期三公布的一份关于国际石油供应状况的关键性报告做出了可怕的预测，它暗示，随着全球经济面临严重的能源紧缺，不久油价将不可逆转地突破100美元一桶的门槛。
14. The ozone layer would be irreversibly damaged.
    臭氧层将会遭到无可挽回的破坏。
15. The evidence is accumulating that prion diseases are due to proteins which change their conformation irreversibly during an association reaction, perhaps by mechanisms related to amyloid accumulation.
    越来越多的证据指出蛋白感染素疾病（如狂牛病）是因为蛋白质结合过程中其构型产生不可逆的改变，可能是由类淀粉体堆积相关的机制造成。
16. They found that many of these acids joined irreversibly with the protein and led to its long term activation.
    他们发现这些酸中有很多和蛋白不可逆地结合，导致PPARgamma长期活化。
17. If we want to turn things around irreversibly, we will not be able to avoid amending the treaties.
    要想扭转危机，并使之不再复发，我们将无法避开条约的修订。
18. Study on the the relative cerebral blood volume of reversibly and irreversibly damaged region in acute cerebral infarction in the rabbit
    论统计物理微观不可逆与宏观可逆的统一兔急性脑梗死可逆/不可逆性损伤区的相对脑血流容积
19. This will help direct surgeons and cardiologists to better target the blood vessels that lead to muscle capable of responding to their therapy, rather than to muscle that is irreversibly diseased.
    从而指导外科医生和心脏病专家更好的靶向营养受损心肌组织的血管，而不是供应已发生不可逆转的损害的肌肉的血管。
20. The nature, evolving irreversibly, is still full of the breathtaking beauty of symmetry.
    不可逆地演进的大自然，依旧充满了令人屏息神往的对称之美。
21. The authors report insufficient evidence to determine the minimally acceptable observation period to ensure that neurologic functions have ceased irreversibly.
    作者说仍然缺乏证据来决定最低限度可接受的观察期间以确保神经功能已经永久消失。
22. Irreversibly inhibits serine proteases by sulfonylation of the serine residue in the active site of the protease.
    通过蛋白酶活性位点丝氨酸残基的磺酰化，不可逆的抑制丝氨酸蛋白酶。
23. Impacted by creep and stress relaxation, the strain of bond coat layer increases irreversibly, and the TGO layer convolutes.
    由于蠕变和应力松弛的影响，粘结层应变不可逆地增加，使TGO层的界面形貌出现起伏。
24. Irreversibly inhibits trypsin but not chymotrypsin by alkylating the histidine residue in the active site of the enzyme.
    通过乙酰化酶活性位点剩余的组氨酸，不可逆的抑制胰蛋白酶（但不含胰凝乳蛋白酶）。
25. Even under this optimistic scenario, however, the world will have changed irreversibly.
    但即使在这种乐观情况下，世界也将发生不可逆转的变化。
26. A current paradigm states that monocytes circulate freely and patrol blood vessels but differentiate irreversibly into dendritic cells ( DCs) or macrophages upon tissue entry.
    目前的模式认为单核细胞可自由循环和巡逻血管，但不可逆的分化成组织入口部位的树突状细胞和巨噬细胞后则失去这种功能。
27. Based on the significant difference of solvency between polysialic acid and irreversibly denatured protein, two processes removing protein from the polysialic acid broth were carried out.
    应用不可逆变性后的蛋白溶解力与聚唾液酸溶解力的显著差异来脱除聚唾液酸发酵液中蛋白质。
28. Breakthroughs in information technology have irreversibly altered the ability to conduct business unconstrained by the traditional limitations of time or space.
    信息科技的突破不可避免地改变了管理商业的能力，而不受到传统的时间和空间的限制。
29. Because the structure of particles will decline irreversibly, mass converts into energy, the reasonable state of time and space field will be affected.
    由于实物粒子结构存在有不可逆转的老化和衰变现象，质量向能量方向转化，时空场结构的有序程度当然要受到不同程度的影响。
30. At 9 months after denervation, the structure of nerve and muscle changed irreversibly.
    面神经损伤9个月，神经和肌肉形态结构都发生了不可逆的变化。

adv

1. in an irreversible manner
   1. this old tradition is irreversibly disappearing