Brown country rice, curried lentils, Jak fruit-the lunch is hearty and generous but I cannot eat. 褐色乡村米饭、咖喱小扁豆,Jak水果-午餐很丰盛,但我却吃不下去。
After being met at the airport by a driver and shuttled to my new accommodations, a member of the JAK production team met up with me. 有司机来机场接我,把我送到我的新住处后,JAK制作组的一个成员来和我见了面。
Influence of leflunomide on JAK/ STAT signal transduction pathway in renal tissue of MRL/ lpr lupus mice 来氟米特对MRL/lpr小鼠肾脏JAK/STAT信号转导途径的影响
Conclusion As an inhibitor of JAK, AG490 can influence the function of normal cells. 结论AG490作为一种酪氨酸激酶抑制剂,能影响正常细胞的功能。
Jak/ STAT signaling pathway of IL-11 in the protection of intestinal epithelial cells from neutron radiation IL-11保护中子照射后肠上皮损伤的Jak/STAT信号转导机制研究
JAK/ STAT signaling pathway and its relationship with tumor invasion and metastasis JAK/STAT信号通路及其与肿瘤侵袭、转移的关系
Progress on JAK/ STATs pathway and pathogenesis of obesity JAK/STATs通路与肥胖发病机制的研究进展
We assumed that the JAK/ STAT pathway may correlate with cardiac damage caused by ischemia-reperfusion and inflammatory factors. 因此,我们推测JAK/STAT通路与缺血/再灌注及炎性因子所导致体外循环后心肌损害均有紧密关联。
Constitutive activation of JAK/ STAT signaling pathway in leukemogenesis 白血病形成中JAK/STAT信号通路的持续激活
Objective To investigate the relationship between the activated JAK/ STAT proteins and the proliferation of myeloid leukemic cells. 目的探索JAK/STAT途径活化与细胞增殖和凋亡之间的关系。
Objective: To investigate the activation of two IL 6 signal transduction pathways JAK/ STAT and Ras/ MAPK/ NF IL 6 in different type of myeloma cell lines and its biological significance. 目的:研究具有不同IL6反应性的人骨髓瘤细胞中两条IL6信号转导途径JAK/STAT和Ras/MAPK/NFIL6的诱导活化情况及生物学意义。
In the meantime, Tec can be regulated by many non-receptor tyrosine kinases such as Src, Jak, Syk and FAK family kinases. 同时,Tec可以被许多非受体型蛋白酪氨酸激酶调节,如:Src、JAK、Syk和FAK家族激酶等。
HGM-CSF receptor is composed of α and β c subunits. It is involved in the Ras/ Raf/ MAPK and JAK/ STAT pathways. hGM-CSF受体由1个α亚基和1个βc亚基组成,它涉及Ras/Raf/MAPK和JAK/STAT途径。
JAK/ STAT-related Gene Expression during Transient Focal Cerebral Ischemia/ reperfusion and during Cell Hypoxia/ reoxygenation 脑缺血和细胞缺氧/复氧过程中JAK-STAT信号转导相关基因的表达
The inhibitory effect on the proliferation of Sko cells mediated by the activation of PKA pathway is temporally related to the inhibition of JAK/ STAT pathway activation by IL 6. Sko细胞中PKA途径激活所介导的细胞增殖抑制作用与IL6的JAKSTAT信号途径的活化抑制作用相关。
Role of JAK/ STAT Pathway in Regulating Myocardial Damage at Early Stage after Ischemia-reperfusion Injury JAK/STAT通路在心肌缺血/再灌注早期损害中的作用研究
Thus, it was proved indirectly that the JAK/ STAT signaling pathway activated by GM-CSF regulated the cell cycle progression through cyclin D1 and cyclin B1 protein. GM-CSF所激活的JAK/STAT信号转导途径通过促进周期蛋白cyClinD1及Cyclinb1的表达而对受辐射细胞周期进行调控。
Objective To investigate the relationship between the activated JAK/ STAT proteins and the proliferation of myeloid leukemic cell. 目的为探索JAK/STAT途径活化与细胞增殖和凋亡之间的关系打下基础。
Role of JAK/ STAT pathway activation in high glucose-induced transdifferentiation in kidney proximal tubular epithelial cells JAK/STAT信号途径在高糖诱导肾小管上皮细胞转分化中的作用
JAK/ STAT is the most important signal transduction pathway of IL-2. JAK/STAT途径是最重要的IL-2信号转导途径之一。
In the past, the studies of JAK/ STAT pathway mainly focused on the hematopoietic system, lymphatic system diseases and tumors, while that on the pathogenesis of RA was still few. 既往关于JAK/STAT信号转导通路的研究大多集中在造血系统、淋巴系统疾病及肿瘤,其在RA发病中的作用研究较少。
This gain-of-function mutation of JAK may explain the hypersensitivity of PV progenitor cells to growth factors and cytokines. 这一功能获得性突变解释了PV患者造血祖细胞对许多生长因子和细胞因子高度敏感的原因。
Through coupling and cytoplasmic tyrosine kinase JAK activating, Leptin receptor realizes signal transduction. 瘦素受体通过偶联和激活胞质酪氨酸激酶JAK(主要是JAK-1和JAK-2)而实现信号转导。
It has been shown that JAK/ STAT signalling is activated after peripheral axotomy and is critical for neuronal regeneration and survival of neurons. 已证明JAK/STAT信号转导是在外周神经细胞轴索切断后被激活的,并且它对神经再生和神经元存活是至关重要的。
At present, some abroad studies have confirmed that JAK/ STAT was activated in the pathogenesis of RA. 目前国外的一些研究已证实,在RA发病过程中JAK/STAT信号通路处于激活状态。
STAT proteins are activated by G-protein coupled receptors, while it has not been reported whether CCK receptors, a kind of G-protein coupled receptors, can activate JAK/ STAT pathway. STAT蛋白可被G蛋白偶联受体激活,而CCK受体作为一种G蛋白偶联受体,是否对JAK/STAT通路具有直接激活作用,尚未见报道。
JAK is a protein phosphatase, the substrate is STAT protein. JAK是一类蛋白磷酸酶,其作用底物为STAT蛋白。