Conclusion The limbic leucotomy can induce the change of central dopamine functional, the content in cortex declined and in subcortex increased, can improve quinpirole-induced compulsive checking in rats. 结论边缘叶脑切开术能降低左侧前额皮质多巴胺含量,增加皮质下结构多巴胺含量,改善QNP处理诱发的大鼠强迫检查行为。
Conclusion Limbic leucotomy and clomipramine can improve compulsive checking in QNP rats. 结论边缘叶脑白质切开术和氯丙咪嗪处理均能明显改善QNP诱发的大鼠强迫检查行为。
The Effect of Stereo Tactic Limbic Leucotomy Lesion on Compulsive Checking Behavior and Dopamine in Rats 边缘叶脑白质切开术对强迫症大鼠行为学改变及中枢多巴胺含量的影响