Preparation of MAbs to Newcastle disease virus and Application in Immunohistochemistry Assay 抗新城疫病毒糖蛋白单克隆抗体的研制及在免疫组化中的应用
Therapeutic mAbs has developed from reshaping antibody and humanized antibody to fully human antibody in order to lower supersensitivity resulting from mouse antibody. 为了降低鼠源抗体引起的超敏反应,治疗性单克隆抗体已由改型抗体,人源化抗体发展到全人抗体。
Eurasian continent is considered to be the best study area for mountain altitudinal belt spectra ( MAbs) researches thanks to its MAbs'magnitude and diversity. 欧亚大陆是山地垂直带谱多样性和复杂性最集中的区域,在世界山地垂直带谱体系中具有十分重要的地位。
In1947, artist Roy Parker and designer Harry Mabs teamed up while working for the Gottlieb pinball company and created Humpty Dumpty, which was the first pinball game to feature flippers. 1947年,艺术家和设计师哈里罗伊帕克单克隆抗体工作时联手为戈特利布弹球公司创建蒂四分五裂,这是第一个弹球游戏功能潜水活动。
Objective To prepare monoclonal antibodies ( mAbs) against multiple antigens by single cell fusion. 目的建立通过单次细胞融合制备抗复合抗原(多种抗原)单克隆抗体的方法。
The reactivity of histones with some MAbs reveals the possible pathogenesis of anti-histones antibody production in autoimmune diseases. 组蛋白与某些单克隆抗体发生的交叉反应性揭示了在自身免疫性疾病中抗组蛋白自身抗体产生的可能致病原因。
AIM: To prepare monoclonal antibodies ( mAbs) against human plasmin α 2 antiplasmin complexes ( PAP). 目的:制备纤溶酶α2抗纤溶酶复合物(PAP)的单克隆抗体(mAb)。
ELISA results showed that the site binding cellular receptor was different from which binding mAbs. 结论干扰素表面细胞受体结合位点与单克隆抗体结合位点是分开的。
Ascites titer, specificity and relative affinity were identified. The titer and relative affinity of ascitic mAbs were determined by ELISA. 测定了单抗的滴度、特异性和相对亲和力。用ELISA检测mAb腹水的效价、相对亲和力和进行表位分析;
All these MAbs showed high hemagglutination inhibition ( HI) activity and neutralizing capacity to the strain. 这6株单抗对NDV都表现出高度的血凝抑制(HI)活性和中和能力。
Western blot was used to assess the reactivity between anti Fc mAbs and denatured Ig fusion protein. westernblot检测mAb对变性Ig融合蛋白的反应性。
Relative characteristics of the mAbs were analyzed by ELISA and immunohistochemical staining. 运用ELISA和细胞免疫组化染色,鉴定mAb的各项特性。
The results of ELISA demonstrated all 11 mAbs reacted with nef peptides and nef proteins, the reaction of No. 3, 7,9, 10 and 11 antibody with nef peptides and nef proteins is similarity. ELISA测定表明,11个单抗均能与nef肽和nef蛋白反应,其中3、7、9、10和11号抗体与nef肽和nef蛋白的反应性相近似;
REPAST, an open source Multi-Agent Based Simulation ( MABS) platform was introduced. 介绍了开放源代码的多Agent仿真(MABS)平台REPAST及其应用现状。
GFP monoclonal antibody can improve the sensitivity of the GFP detection and expand the application of GFP. The GFP mAbs could be very useful in the location of the antigen, purification of fusion protein, interaction between host and pathogen and the development of new detection reagent. GFP单克隆抗体可扩大GFP检测的灵敏度,拓展GFP的应用范围,预计GFP单抗在抗原定位、融合蛋白纯化、病原体与宿主之间相互作用研究以及新型诊断试剂研制等方面具有重要用途。
Objective To prepare specific monoclonal antibodies ( MAbs) against different Mycoplasmas for clinical diagnostics and related research. 目的制备针对临床常见的六种支原体的特异性单克隆抗体,为临床支原体感染检测提供工具。
The mAbs were purified by protein G immunoaffinity method. ProteinG免疫亲合层析法纯化单抗;
The titer and relative affinity of ascitic mAbs were determined by ELISA. 用ELISA检测mAb腹水的效价、相对亲和力和进行表位分析;
The results suggested that two MAbs were probably specific to the common antigen of porcine mycoplasmas. 结果表明两株单抗可能是针对猪支原体共同抗原的单抗。
These results suggested that the binding ability with antigens, inhibition activity to cell-cell fusion, neutralizing ability and activity of mAbs focused on the same epitope could be affected by sequences of different viruses or structures of antibodies. 这些研究结果提示,针对同一表位的单抗,其与抗原的结合能力、抑制膜融合的能力以及中和能力和中和活性也可能受到病毒株本身序列及抗体空间结构的影响。
All the mAbs have κ-light chain of immunoglobulin. 所有单抗的轻链均为κ链。
Monoclonal antibodies ( mabs) against daintain/ AIF-1 and insulin production. 制备daintain/AIF-1和胰岛素的单克隆抗体。
The immunoglobulin subclass of the 4 mAbs were IgG1. 四株单抗的免疫球蛋白亚类均为IgG1。
The MAbs reacted specifically with the corresponding antigen, and there were no cross reaction between the monoclonal antibodies. 这些单克隆抗体对相应抗原表现出高度特异性,相互之间不存在交叉反应。
The results showed that thirteen MAbs could recognize the different epitope on E protein. 研究结果表明13份E蛋白单克隆抗体可识别其不同的抗原表位蛋白。
MAbs have been used to impart selectivity to otherwise indiscriminately cytotoxic agents such as toxins, radionuclides. 单抗一直被用来给予其他无选择性的细胞毒药物诸如毒素、放射性核素的选择能力。