Langer likes to point out that minoxidil was a failed hypertension medication with the miserable side effect of unwanted hair growth. Researchers forgave themselves long enough to find meaning in the failure by developing Rogaine from it. 兰格指出,米诺地尔(毛发生长刺激药物总称)是在治疗高血压的药物造成不必要的毛发生长的副作用中发现的。研究人员通过发明落健(药品名)在这一失败中找到了意义。
Determination of Minoxidil in Minoxidil Liposomes Alcohol by HPLC HPLC法测定米诺地尔醇脂质体中米诺地尔的含量
The Clinical Observation of Simple Hairs Auto-transplantation Combined with Minoxidil Application in Patients with Hair Loss 简易毛发移植联合外用米诺地尔酊治疗毛发缺稀的临床观察
Objective: To develop a preparing method and quality control for minoxidil solution. 目的:探讨米诺地尔生发液的制备方法及质量控制。
AIM To investigate the best concentration of the combination of ginseng extract and minoxidil by the culture of mouse follicle in vitro. 目的通过小鼠体外毛囊培养,探讨复方米诺地尔制剂中米诺地尔和人参提取物的最佳浓度;
Determination of content of minoxidil of compound minoxidil solution 复方米诺地尔溶液中米诺地尔的含量测定
The effect of minoxidil on human hair growth in vitro 米诺地尔对培养人头皮毛囊生长的影响
Effects of azone on transdermal absorption of ginsenoside Rg_1 and minoxidil 氮酮对人参皂苷Rg1和米诺地尔透皮吸收的影响
Evaluation of randomized double blind placebo controlled topical minoxidil in male pattern baldness 米诺地尔治疗男性型秃发的疗效评价
Minoxidil treatment in maintenance hemodialysis patients with refractory hypertension 米诺地尔在治疗血液透析伴顽固性高血压中的应用
CONCLUSION The method can exclude disturbance, it can be an index of quality control of compound minoxidil solution. 结论该法能排除干扰,可作为复方米诺地尔溶液质量控制的有效方法之一。
Study of Compound Minoxidil on the Mouse Hair Growth 复方米诺地尔对鼠毛生长作用的研究
AIM To determine content of minoxidil in compound minoxidil solution and provide an index of quality control. 目的测定复方米诺地尔溶液中米诺地尔的含量,为该药提供质量控制指标。
We study the security of the combination of ginseng extract and minoxidil with acute toxicity trial, stimulation trial and hypersensitivity trial on animal skins which provide the foundation for clinical application. 通过对动物的皮肤急性毒性试验、皮肤刺激性试验及皮肤过敏性试验观察复方米诺地尔的安全性,为临床用药提供依据。
Nifedipine, a calcium antagonist, and minoxidil, a potassium opener, could inhibit the licking response and prevent the decrease of histamine content in the skin induced by 4-AP. 钙拮抗剂硝苯啶与钾通道开放剂米诺地尔均能抑制4-AP诱发的小鼠舔体反应,且给4-AP部位,皮肤组胺含量明显高于对照组。
The histologic results showed 1.4% lipo-minoxidil group, 2% minoxidil group and 1.4% minoxidil group all were anagen hair follicles, but the cntrol group and blank group were telogen. 皮肤组织学观察1.4%脂质体米诺地尔组、2%米诺地尔组和1.4%米诺地尔组均处于典型的生长期毛囊,而空白脂质体组和空白组毛囊处于休止期;
A major challenge for the revealment of molecular mechanism is to establish a satisfied model. First, The effects of Minoxidil on hair follicle cycle and the possible mechanisms were investigated in hair follicle whole-organ culture model. 对其分子机制的研究困难在于难以获得满意的模型。因此,本研究首先通过毛囊体外器官型培养的模型探讨了敏乐定在毛囊周期中的作用以及可能机制。