And the cheapness of modern gene-sequencing methods, particularly those that are looking for specific mutations suspected in advance, means that a tumour's mutational complement can be worked out easily in an appropriately equipped pathology laboratory. 而且,现代基因测序法价格低廉,寻找预先已有怀疑的某些特别的基因突变尤为便宜;这意味着,在拥有合适装备的病理实验室里,人们可以很容易地找出肿瘤基因突变的补体。
Objective: To observe the mutational pattern of STR loci in parentage testing cases. 目的:观察亲子鉴定中STR基因座的突变方式。
Expressional and Mutational Analysis of Pro-apoptotic PUMA in Non-small-cell Lung Cancer 促凋亡基因puma与非小细胞肺癌的相关性研究
Mutational analysis of ARID1A was carried out in selected cases. 我们在经过筛选的病例中分析了ARID1A基因的突变情况。
Cancer is caused by mutational damage to genes that otherwise hold a cell's reproductive cycle in check, and thus stop that cell proliferating. 癌症是由于基因变异产生的,它控制了细胞的再生,阻止细胞的分裂。
These large populations facilitate the detection of rare mutational or recombinational events. 这样的大群体有利于检出稀有的突变或重组子。
Doramectin, which is manufactured by mutational biosynthesis method, is a novel avermectin derivative. Years of attempting to cure the disease with antibiotics and quinine drugs have caused the parasite to become resistant to treatment. 道拉菌素是利用生物突变合成方法得到的新型阿维菌素族广谱抗寄生虫药。多年来使用抗生素和奎宁治疗这种疾病的努力导致那些寄生虫产生了抗药性。
Mutational and Expressional Analyses of the Transforming Growth Factor Beta Type ⅱ Receptor Gene in Primary Non-small Cell Lung Cancer 非小细胞肺癌TGF-βⅡ型受体基因突变和表达研究
Optimization of PCR Amplification Parameters for Mutational Hotspots in the Human Catalase Gene CAT基因突变热点区域的PCR扩增方法
Rapid detection of high frequency mutational sites of Chinese Wilson's disease gene 中国人Wilson病患者基因高频突变位点的快速检测
By introducing the nonlinear variation weight and mutational operation into the standard particle swarm algorithm to ensuring the overall convergence and enhance the accuracy of convergence. 在标准粒子群算法中引入非线性变化权重和变异操作来保证全局收敛并提高收敛精度。
Mutational Analysis of Thyroid Transcription Factor-1 Gene and Investigation on Its Expression in Lung Carcinoma 肺癌甲状腺转录因子-1基因突变及表达规律研究
Mutational Screening of White Rot Fungi for Laccase Production in Liquid Cultivation 产漆酶白腐菌的诱变选育及其液体发酵的研究
Conclusion Heteroduplex-SSCP analysis is simple, economical and more effective than SSCP or heteroduplex analysis alone and it may be widely applied in mutational screening. 结论异源双链-SSCP法突变检出率高,经济、简便,值得在基因突变筛查中推广应用。
Mutational Analysis of Complement Factor H Gene in Children with Sporadic Atypical Hemolytic Uremic Syndrome in Chinese Han Ethnic Group 中国汉族散发性溶血尿毒综合征儿童CFH基因突变分析
It is "difficult to imagine any simple set of mutational events that could bring about resistance", says Kelly. “很难想象任何一组简单的突变事件可以带来(针对它的)耐药性,”Kelly说。
Conclusions Genotypes defined by the mutational status of NPM1, FLT3, CEBPA, and MLL are associated with the outcome of treatment for patients with cytogenetically normal AML. 结论:由NPM1,FLT3,CEBPA,和MLL基因的突变状态所界定的基因型与细胞遗传学正常的急性髓细胞白血病患者的临床治疗结局之间存在相关性。
The Mutational Biosynthesis of Doramectin and Studies on the Fermentation Condition 多拉菌素的突变生物合成及发酵条件优化
Attenuation of Epidemic Marek's Disease Virus Strains in Vitro and Mutational Analysis of Main Tumor-associated Genes 马立克病毒流行毒株致弱及主要致瘤相关基因变异分析
Mutational Study of Exon 12 of Glutamate Receptor δ 2 Gene in Patients with Cerebellar Ataxia 小脑性共济失调症患者谷氨酸受体δ2基因12号外显子突变研究
It also introduces the concept of function module and a new kind of coding way, crossover operator and mutational operator. 提出了功能块的概念,介绍了一种新的编码方式、交叉算子和突变算子。
The expression of variants and mutational status was investigated with RT PCR and direct DNA sequencing. RT-PCR/DNA测序技术检测基因突变和变异体的表达。
Detecting and identifying mutational signal is very critical when we detect states and analyze fault signal of device. 在对设备进行状态检测和故障信号分析时,突变信号的检测和识别是很关键的。
In this paper, the progress, especially combining gene engineering of mutational biosynthesis is reviewed. 本文综述了突变生物合成技术在微生物药物领域的应用,特别是结合基因技术进行突变生物合成研究的新进展。
The results show it can achieve higher rate of mutation and wider mutational spectrum. 结果表明能获得较高的突变率和较广的突变谱。
The HBV gene mutational sites of pre-C and BCP regions were assayed by using technology of gene chip. HBV前C区和BCP(基础核心启动子)区基因位点变异采用HBV基因多态性芯片进行检测。
This study provides a quantitative and mechanistic explanation of mutational effect from detailed analyses of the structure-affinity relationship. 利用结构与亲和能关系的分析对变异所产生的抗药性进行了定量的和力学的解释,而且与实验分析相一致。