Effect of cardiac chymase on cardiac myofibrosis in spontaneously hypertensive rats 心脏糜酶在自发性高血压大鼠心肌纤维化中的作用
The pretreatment of SPC followed by CP can prevent and relieve the development of myofibrosis and CGA. SPC和CP联合预处理,可以预防和减缓移植心脏心肌纤维化和心脏动脉硬化。
The role of transforming growth factor β_1 in left ventricular myofibrosis in rats with furazolidone-induced dilated cardiomyopathy 转化生长因子β1在扩张型心肌病大鼠心肌纤维化中的作用
Conclusions; The results suggest that PC ⅲ, LN and HA may act as serum markers for myofibrosis cordis in hypertensive patients with LVH. 结论:血清PCⅢ、LN、HA可以作为高血压左室肥厚患者心肌纤维化的观察指标。
To investigate the value of serum hyaluronic acid ( HA), laminin ( LN) and type ⅲ procollagen ( PC ⅲ) levels in essential hypertensive patients on myofibrosis cordis, two dimensional echocardiography was performed to determine left ventricular mass index ( LVMI). 检测血清Ⅲ型前胶原(PCⅢ)、层粘连蛋白(LN)和透明质酸(HA)的水平与研究其对高血压心肌纤维化患者的临床价值。
Partial myofibrosis; atrophy of mucosa; hyperemia and edema of submucosa; 主要表现为乙状结肠肠壁肥厚,部分肌纤维变性,结肠黏膜萎缩,黏膜下充血水肿;
Conclusion: This study supports the hypothesis that the cardiac chymase may increase collagen synthesis and participate the formation and degradation of extracellular matrix in myocardial tissue and accelerate cardiac myofibrosis in spontaneously hypertensive rats. 结论:心肌组织糜酶参与胶原的合成,参与细胞外基质的形成和降解,促进自发性高血压大鼠心肌纤维化。
Objective To investigate the effects of simvastatin ( Sim) on the proliferation of rat cardiac fibroblasts ( CFs) induced by arginine vasopressin ( AVP) for theoretical bases of preventing and treating cardiac myofibrosis due to hypertention. 目的探讨辛伐他汀(Simvastatin,Sim)对血管升压素(AVP)诱导的新生SD大鼠心脏成纤维细胞(CFs)增殖的影响,为防治高血压心肌纤维化提供理论依据。
Myofibrosis mechanism of differentiation growth factor-8 on rat abdominal aorta grafts 分化生长因子-8对大鼠移植腹主动脉肌纤维化的作用及其机制
Objective: To evaluate the effect of cardiac chymase on collagen synthesis in myocardial tissue and cardiac myofibrosis in spontaneously hypertensive rats. 目的:观察心脏糜酶对自发性高血压大鼠(SHR)心肌组织胶原合成和心肌纤维化的影响。
Objective To investigate the role of differentiation growth factor-8 ( GDF-8) in inhibiting myofibrosis of abdominal aorta grafts. 目的探讨分化生长因子(GDF)-8对移植大鼠腹主动脉肌纤维化的抑制作用。