Unlike with other drug-induced myopathies, serum CK concentration does not markedly increase with steroid myopathy. 与其他药物诱导肌病不同的是,类固醇肌病不引起血清CK浓度明显升高。
Research progress on functional exercises for patients with idiopathic inflammatory myopathies 特发性炎性肌病病人功能锻炼研究进展
The presence of these immune cells and processes suggests revisions in models of the pathogenesis of the inflammatory myopathies and provides rationales for future therapeutic approaches. 这些免疫细胞和免疫过程的存在修订炎性肌病发病机制模型,为今后新的治疗方法提供了依据。
Methods Ten cases of patients with polymyositis and 6 patients with other myopathies were collected. CD 34, ICAM-1 and IL-1 α were selected for a quantitative measurement using an image analysis system, and results were presented as the percent of positive staining in the tissue area. 方法收集10例多发性肌炎患者和6例非炎性肌病,采用图像分析法计算CD34、ICAM1、IL1α阳性微血管面积与面密度,进行定量分析和比较。
Evaluation of lipid accumulation in muscle fibers in inflammatory myopathies 肌纤维内脂滴增多在炎性肌病中的意义
In this paper the fundamental pathological and ultrastructural changes in skeletal muscle were described with emphasis on the diagnostic electron microscopy of myopathies. 本文介绍了肌病的基本病理变化和主要超微结构改变,以及电镜诊断中应注意事项。
Conclusion CT is valuable for differentiation between neurogenic and myogenic muscular disorders. The myopathies on CT could be divided into 4 stages according to the degree and extent of the muscular lesion. 结论CT有利于鉴别诊断神经源性及肌源性疾病,并根据CT表现将肌变性的范围及程度分为4期。
Compared with the cases not began with pulmonary abnormities, the clinical features of extra-pulmonary, such as inflammatory myopathies, polyarthritis/ polyarthralgia, fever, mechanician hands, Raynaud ′ s phenomenon, showed insignificant statistical difference, except typical DM rash. 与非肺部表现起病的其他病例比较,除典型DM皮疹外,其余肺外临床特征如炎性肌病、多关节炎/关节痛、发热、技工手、雷诺现象等均无统计学差异;
KL-6 as a useful serum marker for interstitial lung disease in patients with idiopathic inflammatory myopathies 血清KL-6检测在特发性炎性肌病伴肺间质病变诊断中的价值
Rare Immune-related Myopathies 罕见免疫源性肌病
Collagen synthesis and degradation in polyneuropathy and myopathies 多发性神经病与肌病患者胶原蛋白的合成与降解
Ultrastructural pathological diagnosis of metabolic myopathies 代谢性肌病的超微病理诊断
Objective To investigate the ultrastructural changes of4 different types of congenital myopathies. 目的探讨不同类型的先天性肌病的超微结构变化规律。
Pathological types of muscle biopsy from patients with idiopathic inflammatory myopathies: a retrospective clinicopathologic analysis of 119 cases 特发性炎性肌病119例肌肉活检病理分析
Lactate production upon short-term non-ischemic forearm exercise in mitochondrial disorders and other myopathies 线粒体病和其他肌病患者短期非缺血性前臂训练后的乳酸生成
Idiopathic inflammatory myopathies are a group of heterogeneous chronic inflammatory disorders clinically characterized by proximal skeletal muscle weakness and muscle fatigue, and histologically featured by mononuclear inflammatory cell infiltrates in the muscle tissues. 特发性炎性肌病是一组异质性慢性炎性疾病,临床特点是近端骨骼肌无力和肌肉疲劳,组织学特点是肌肉组织中单核炎性细胞浸润。
Giving clinical comprehensive analysis on all the grouped metabolic myopathies patients above, the observation index includes: clinical manifestations, blood biochemical, electric physiology and pathology features. 2. 方法1.对所有入组的患者进行临床综合分析,观察指标包括:血生化、电生理及病理指标。
Moreover, the level of these cytokines was found correlated with the muscle dysfunction in the patients with idiopathic inflammatory myopathies. 而且,人们进一步发现这些细胞因子的水平与特发性炎性肌病患者的肌肉功能障碍相关。
The AMA expression has important value in metabolic myopathies diagnosis, which also offers a new path for it. 3. AMA的表达检测在代谢性肌病的诊断中具有重要价值,为代谢性肌病的诊断提供了一条新路径。
Anti-MHC class ⅰ molecule, CD8 molecule monoclonal antibody immunohistochemistry stains pathological analysis on the basis of skeletal muscle biopsy histochemical stains show considerable significance for the typing diagnosis and differential diagnosis between IIM and other myopathies. 在骨骼肌活检组织化学染色基础上行抗-MHC分子、CD8分子单克隆抗体免疫组织化学染色病理分析对IIM分型诊断和与相关肌病的鉴别诊断具有重要价值。
Because of the biological function of myostatin, it has raised the possibility of using its regulators or soluble receptor to promote muscle growth and improve the disease phenotypes in a variety of myopathies, including the muscular dystrophies and degenerative and metabolic diseases. 由于这种生物学功能,使得其抑制因子或可溶性受体在促进肌肉的生长,以及肌营养不良、肌肉退行性或代谢性疾病等疾病的治疗中得到应用成为可能。