Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. 连续多巴胺转运蛋白显像与特发性快动眼睡眠行为障碍患者的黑质纹状体功能:一项前瞻性研究。
Acute damage of nigrostriatal system in MPTP-treated senescence accelerated mouse and damage-related microglial activation MPTP对快速老化小鼠黑质纹状体系统的急性损害及小胶质细胞的激活
The results imply that nigrostriatal dopaminergic system regulates the functions of somatostatin neurons in the striatum of the rat at the level of gene transcription. 结果提示黑质纹状体多巴胺神经系统在基因转录水平调节着纹状体中SOM神经元的功能活动。
Thirty-four female albino rats of Holtzman strain were observed in this experiment as models of rotational behavior with unilateral 6-hydroxydopamine ( 6-OHDA) lesions of the nigrostriatal system in the brain. 本实验观察了Holtzman种系雌性大白鼠34只。以6-OHDA制备单侧大脑黑质纹状体系统损伤的旋转行为模式。
Correlation between iron levels and degeneration of dopaminergic neurons in rat nigrostriatal system during the early 6-OHDA lesions in medial forebrain bundle 6-羟基多巴胺损毁大鼠内侧前脑束早期黑质-纹状体系统的铁水平与多巴胺能神经元退变的关系
Effect of nigrostriatal dopaminergic lesions by 6-hydroxydopamine on somatostatin neurons in the forebrain were studied by in situ hybridization histochemistry and immunocytochemistry. 本实验用原位杂交组化和免疫组化方法研究了黑质纹状体多巴胺系统被6-羟基多巴胺损伤后对前脑SOM神经元的影响。
Crossed nigrostriatal projection in rats 大鼠黑质&纹状体对侧投射
The participation of iron-induced oxygen free radicals in the process of nigrostriatal dopamine neuron degeneration is strengthened by recent studies in which the neurotoxicity of 6-OHDA had been linked to the release of iron from its binding sites in ferritin. 最近对6-羟基多巴的神经毒性与其能从铁蛋白中释放铁的有关研究,更加证实了铁诱导产生氧自由基参与黑质纹状体多巴胺能神经元变性。
Experimental study of neurotoxic effect of iron ion on nigrostriatal dopaminergic neurons 铁离子对黑质纹状体多巴胺神经元毒性作用的实验研究
Parkinson Disease ( PD) is a kind of progressive neural degeneration of nigrostriatal system. 帕金森病(PD)是锥体外系统的进行性神经变性疾病,其发病机制有多种学说。
Quantitative evaluation of the nigrostriatal projection in multiple system atrophy by MR diffusion tensor imaging: a preliminary study 磁共振扩散张量成像用于多系统萎缩患者黑质纹状体投射的初步研究
Administration of 1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine ( MPTP) to mammals causes damage to the nigrostriatal dopaminergic pathway similar to that observed in Parkinson's disease. 1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)能够诱发黑质纹状体系统多巴胺能神经元损伤并产生与帕金森病类似的症状。
Response of nigrostriatal neurons to 20 Gy ionizing irradiation and intervening effect of nimodipine 20Gy电离辐射后黑质纹状体系统的神经元反应及尼莫地平的干预作用
Pathological changes are dopaminergic neurons degeneration and apoptosis of the nigrostriatal area in the midbrain and the formation of lewy small body. 病理改变为中脑黑质纹状体区多巴胺能神经元变性凋亡和lewy小体形成为特征。
Comparison of each group were positive for TH protein expression and to explore the distribution of dopamine nigrostriatal function repair. 分别比较各组TH蛋白的阳性表达及多巴胺含量分布情况探索黑质纹状体功能修复情况。
In this study, 6-hydroxydopamine ( 6-OHDA) was microinjected into one side of the nigrostriatal system of the brain to generate a PD animal model through the impairment of rats dopaminergic neurons. 本研究利用6-羟基多巴胺(6-OHDA)微量注入脑内单侧黑质纹状体系统,通过损毁大鼠多巴胺能神经元制作PD动物模型,观察PD大鼠ENS中神经递质的改变对胃肠功能的影响。