nondisjunction

1. Aneuploidy The condition, resulting from nondisjunction of homologous chromosomes at meiosis, in which one or more chromosomes are missing from or added to the normal somatic chromosome number.
   在减数分裂的过程中同源染色体不分离而造成的一条或多条染色体的缺失或增加。
2. STR-PCR technique was used to amplify 4 loci on chromosome 21, 3 loci on chromosome 18 and 3 loci on chromosome 13 to diagnose those chromosomal trisomies as well as the parental origins of the extra chromosomes and the stages of nondisjunction.
   采用STR-PCR技术，扩增21号染色体4个位点；18、13号染色体各3个位点，诊断这些染色体三体综合征，与染色体核型对照：并判断额外染色体双亲来源和染色体不分离发生时期。
3. Nondisjunction of chromosome 21 is much more frequent than loss in vivo and in vitro.
   21号染色体不分离与年龄的关系极显著，无论在体内还是体外，21号染色体不分离远远高于丢失。
4. Diagnosis of Common Trisomies and Identification of Parental Origins of Extra Chromosomes and Stages of Nondisjunction by STR-PCR Analysis
   STR-PCR分析诊断常见染色体三体及其亲源性、染色体不分离时期
5. Maternal nondisjunction was demonstrated in 14 cases, ten cases were due to nondisjunction in the first meiotic division and 4 cases were caused by nondisjunction during the second meiotic division.
   证明为母源的14例（73.7%），其中10例是第一次减数分裂不分离，4例是第二次减数分裂不分离。
6. In aneuploidy detection test TNT did not induce X and Y chromosomal nondisjunction, but induced the loss of X or Y chromosome with a good dose-response relationship.
   在非整倍体检测实验中，X或Y染色体丢失率明显增加，也有明显的剂量反应关系。说明TNT对果蝇生殖细胞具有明显的致突变作用。
7. Conclusion: The twin girls originate from dizygotic and the extra chromosome 21 of the elder sister is from nondisjunction during the first meiotic division of the mother.
   结论孪生姐妹为异卵孪生，孪生姐姐额外的21号染色体来自于母亲第1次减数分裂不分离。
8. Conclusion Both nondisjunction, balanced and unbalanced predivision of chromatids are involved in the oocyte aneuploidy formation.
   结论同源染色体不分离和姐妹染色单体平衡性及非平衡性过早分离这三种机制均参与了卵细胞非整倍体的产生。
9. The variations of CKC may be the main reason for the chromosomal nondisjunction during meiosis that is attributed to the adverse pregnancy.
   CKC变异频率增高可能是导致不良孕产非整倍体形成的主要原因之一。
10. For wall reactors, higher heat efficiency attributes to nondisjunction of reaction and heat transfer zone.
    壁反应器的反应表面和换热表面不分离，具有较高的热量耦合效果；
11. Conclusion: The parental origin of the extra chromosome 21 can be detected in most Down syndrome using these three loci, and this experiment is helpful to illustrate the mechanism of chromosome nondisjunction.
    结论：根据这3个遗传标记可确定大多数先天愚型患儿额外染色体的双亲起源，为研究染色体不分离的机制奠定基础。
12. Study on meiotic nondisjunction in Leymus chinensis phenomenon
    羊草减数分裂不分离现象的研究
13. This Ha-ras allele loss may have resulted from a mitotic nondisjunction or a mitotic recombination event.
    这一现象可能是有丝分裂不分离或重组事件造成的，它提示Ha-ras在胃癌中的激活除点突变外还有另外的途径。
14. Objective: To study the variation of X chromosome centromeric Alpha Satellite DNA in Klinefelter's syndrome patients, their parents and normal individuals and to discuss the mechanism of Klinefelter's syndrome X chromosome nondisjunction.
    目的：本文从DNA分子水平对Klinifelter综合征患者及双亲X染色体着丝粒区域的α-卫星DNA变异进行研究，探讨Klinefelter综合征患者X染色体不分离形成的原因。

noun

1. meiosis in which there is a failure of paired homologous chromosomes to separate