Effects of open heart surgery under normothermic and hypothermic cardiopulmonary bypass on cytokines and complements 常温与低温体外循环心脏直视手术对细胞因子及补体的影响
Results: Hypothermia significantly inhibited the release of glutamate and glycine, therefore the high excitotoxic index seen in the normothermic group was strikingly decreased in the hypothermic group. 结果:低温明显抑制了细胞外谷氨酸、甘氨酸浓度的升高,使兴奋毒性指数显著降低。
Effects of Normothermic Cardiopulmonary Bypass on BDNF mRNA Expressions in Hippocampi of Rats 常温体外循环对大鼠海马BDNFmRNA表达的影响
Objective To explore the expression of apoptosis-regulating genes C-jun and Bcl-XI, after normothermic liver ischemic preconditioning and its protective effects on hepatocytes in rats. 目的探讨常温下大鼠肝脏缺血预处理对细胞凋亡调节基因C-jun和Bcl-XL的表达及其对肝细胞的保护作用。
Experimental study on the tolerance of normothermic hepatic inflow occlusion with portal blood bypass in rat 门静脉转流下大鼠耐受入肝血流阻断安全时限的实验研究
The use of normothermic blood and cardioplegia perfusion on myocardium preservation 常温血停搏液灌注心肌保护技术的临床应用
Objective To examine the effects of propofol, midazolam and pyrrolidine dithiocarbamate ( PDTC) on acute lung injury ( ALI) induced by normothermic cardiopulmonary bypass ( CPB). 目的观察异丙酚、咪达唑仑及吡咯烷二硫代氨基甲酸酯(PDTC)对大鼠体外循环(CPB)后急性肺损伤(ALI)的影响。
Functional evaluation of normothermic ischemia and reperfusion injury in dog kidney by using MR perfusion-weighted imaging MR灌注成像评价犬肾缺血再灌注损伤的功能变化
Objective To investigate the changes of hepatic portal vein blood flow ( PBF) and oxygen metabolism during normothermic or hypothermic cardiopulmonary bypass ( CPB). 目的研究常温和低温心肺转流(CPB)期间门静脉血流量(PBF)和氧代谢的变化。
Methods The tail artery serving as the arterial inflow and the right jugular vein as the venous drainage for the CPB circuit, we established the normothermic CPB model in SD rats. 方法以SD大鼠为研究对象,尾动脉插管灌注,右颈静脉插管引流,建立常温大鼠体外循环模型。
Normothermic blood and cardioplegia have been used for myocardium preservation in 74 cases undergoing open heart operations. 采用常温血停搏液灌注心肌保护技术施行74例心内直视手术。即在常温血高钾停搏液灌注使心脏停跳后,用温血停搏液连接灌注心肌,使心肌得到最佳保护。
Objective: To explore the effect of purine nucleoside phosphorylase ( PNP) activity and exogenous hyaluronic acid ( HA) absorption after cold storage and normothermic reperfusion in rats with liver ischemia/ reperfusion injury. 目的:探讨嘌呤核苷磷酸化酶(PNP)活性和外源性透明质酸(HA)吸收率对大鼠肝脏低温保存及常温缺血再灌注损伤的作用。
Objective Determining the respective incidence, risk factors and prognosis of hyperuricemia post normothermic cardiac surgery with cardiopulmonary bypass. 目的探讨体外循环直视心脏手术后高尿酸血症的发生率、危险因素及其对病人预后的影响。
Results It is feasible to establish the normothermic CPB model in SD rats. The rats remained alive during CPB with a high flow rate ( 200ml · min-1 · kg-1). 结果现有条件下能够建立常温大鼠体外循环模型,较高流量(200ml·min~(-1)·kg~(-1))转流1h,转流期间保持存活,但容易出现代谢性酸中毒和动脉血压降低;
Conclusion The normothermic is more physiologic status than hypothermia in bypass and monitor the changes of lactate during bypass is helpful for management bypass good cellular perfusion, and less complications postoperatively. 结论常温转流要较低温转流更符合生理、血浆乳酸水平检测,有助于随时调整转流管理策略,使组织灌注在较佳状态,减少转流后并发症。
The change of oxygen free radical during hepatic normothermic ischemic reperfusion and cold preservation in the rat 大鼠肝脏缺血再灌注及低温保存过程中氧自由基变化的实验研究
Conclusion Postischemic hypothermic perfusion as long as 60 minutes has no adverse effect on recovery of myocardial function after normothermic global ischemia. 结论心肌缺血后低温灌注对心肌的缺血再灌注损伤无加重作用,体外循环心脏直视手术后的低温灌注期对心功能恢复无不良影响。
Conclusions ( 1) Ischemic preconditioning can protect the rat liver from normothermic ischemic reperfusion injury by modulation of the expression of apoptosis-regulating genes C-jun and Bel-XL. 结论①缺血预处理通过调节肝细胞凋亡调节基因C-jun和Bcl-XL的表达,发挥其对大鼠常温下肝脏缺血再灌注损伤的保护作用;
Modified hepatectomy with total hepatic vascular blockade under normothermic status 改良式常温下全肝血流阻断切肝术
Objective To investigate the value of systemic normothermic/ cardiac hypothermic cardiopulmonary bypass ( CPB) to the operation of congenital heart disease. 目的探讨全身常温、心脏局部低温体外循环(CPB)在先天性心脏病直视手术治疗中的应用价值。
Myocardial protective effects of normothermic induction and warm blood cardioplegia perfusion before aorta declamping 温血诱导心脏停搏和主动脉开放前温血灌注的心肌保护作用
Results During the encephalic ischemia, the glutamic acid and nitric oxide at different time of the mild hypothermic group were all lower obviously than that of the normothermic group. 结果在脑缺血期间,亚低温组不同时点上谷氨酸及一氧化氮水平均明显低于正常体温组。
The changes of hepatic portal vein blood flow and oxygen metabolism during normothermic or hypothermic cardiopulmonary bypass 常温和低温心肺转流期间门静脉血流量及氧代谢的变化
The experience of liver resection in normothermic first hepatic portal intermittent ischemia 常温下第一肝门血流间歇阻断行肝叶切除的体会
An experimental study on prevention of liver injury during normothermic ischemia and reperfusion 常温肝脏缺血再灌注损伤防治的实验研究
The potentialities for myocardial protection with continuous normothermic oxygenated crystalloid cardioplegia ( CNOCC) and intermittent hypothermic anaerobic crystalloid cardioplegia ( IHACC) were compared and evaluated with the isolated rat heart working model. 采用离体鼠心工作模型,比较并评定了常温充氧晶体停搏液连续灌注和低温乏氧晶体停搏液间断灌注对心肌保护作用的效果。
Objective: To study the influence of ultramicroscopic structure by different way of normothermic hepatic vascular exclusion in canine. 目的:研究犬常温下不同方法阻断入肝血流对肝超微结构的影响。