Objective To study the molecular epidemiological profiles of Brucella infection in China, the method of hypervariable octameric oligonucleotide finger-prints ( HOOF-Prints) analysis was established. 目的应用高变八聚体寡核苷酸指纹(hypervariableoctamericoligonucleotidefingerprints,HOOFPrints)分析法对我国的布氏杆菌进行亚型和分子流行病学的研究。