oligonucleotides
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网络 寡核苷酸类; 寡核苷酸; 寡聚核苷酸; 寡核甘酸; 寡核苷类化合物
双语例句
- Experimental research on therapy of adenocarcinoma cells and athymic mouse model with MMP-9 antisense oligonucleotides
MMP-9反义寡核苷酸对肺腺癌细胞及其裸鼠移植瘤治疗的实验研究 - Antitumor effect of CpG oligonucleotides on human neuroblastoma xenografts in nude mice
含CpG寡核苷酸在人神经母细胞瘤裸鼠移植瘤模型中的抗肿瘤效应 - Fluorescence quenching of TMR by guanosine in oligonucleotides
寡聚核苷酸中鸟苷对四甲基罗丹明的荧光猝灭 - Fluorescent Recognition of Single-and Double-Stranded Oligonucleotides Based on Rhodamine B-Modified Self-assembled Bilayers
基于核酸高级结构自组装的功能模拟研究罗丹明B自组装膜对单、双链脱氧核糖核酸的荧光识别 - Inhibitory Effect of Oligonucleotides Containing CCT on TLR7/ 9 Mediated Innate Immune Response
含CCT基序的寡核苷酸对TLR7/9介导的天然免疫应答的抑制作用 - Preliminary researches for the method of separation of oligonucleotides with difference of a single base in sequence from each other by non-gel sieving capillary electrophoresis;
本文首次将这一技术应用于阳极电泳涂装过程，系统探讨了电泳工艺参数对涂膜性能的影响。 - Analysis of Fluorescent Dye-labeled Oligonucleotides by Ion Pair Reversed Phase High Performance Liquid Chromatography
荧光标记寡核苷酸的反相离子对色谱分析 - Vascular endothelial growth factor antisense oligonucleotides inhibition of bladder carcinoma in nude mice mediated by ultrasound microbubble
超声微泡介导血管内皮生长因子反义寡核苷酸抑制裸鼠膀胱肿瘤 - Colorimetric detection of melamine using gold nanoparticles capped with oligonucleotides
寡聚核苷酸标记纳米金可视化检测三聚氰胺 - To study cholesterol polyamine conjugates as a delivery system of antisense oligonucleotides
多胺胆固醇缀合物纳米粒作为反义核苷酸传递系统的研究 - As compared to conventional drugs that work on proteins, antisense oligonucleotides work on RNA.
与传统的作用于蛋白质的药物相比，反义寡聚核苷酸作用于RNA。 - Effect of Antisense Oligonucleotides Targeting TNF-α on Murine HSV-1 Retinitis
肿瘤坏死因子α反义寡核苷酸对鼠单疱病毒性视网膜炎的影响 - Important new applications that could not be performed using natural oligonucleotides have emerged.
许多重要的、用天然寡核苷酸无法实现的新应用也应运而生。 - Results: The abilities of antisense oligonucleotides to inhibit the cell growth of KB-A-1 mainly depended upon their targeted sequences selected.
结果：作用靶点不同的反义寡核苷酸对KB-A-1细胞生长的抑制能力不同。 - The aim of gene therapy is to transfect DNA into target cells, in which utilizing antisense oligonucleotides is a main method.
基因治疗是将DNA转染进入目的细胞，修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。 - Inhibition of IGF-1R antisense oligonucleotides on FDM in the guinea pig
胰岛素样生长因子1受体反义寡核苷酸对豚鼠形觉剥夺性近视眼的抑制作用 - The Effects of Antisense Oligonucleotides bcl-2/ bcl-xl and bcl-2 on Proliferation and Apoptosis of Breast Cancer Cells
bcl-2/bcl-xl和bcl-2反义寡核苷酸对乳腺癌细胞增殖和凋亡的影响 - Inhibition of Hepatocellular Carcinoma Cell Proliferation by Antisense Oligonucleotides Targeting the Messenger RNA Encoding Proliferation Cell Nuclear Antigen
增殖细胞核抗原反义核酸对人肝癌细胞增殖的抑制作用 - Effect of Antisense Oligonucleotides Targeting Cyclooxygenase-2 on Cytology and C-myc Gene Expression in Colo-16 Cells
COX-2反义寡核苷酸对Colo-16细胞生长及c-myc基因表达的影响 - However, unlike most of the DNA and RNA oligonucleotides, PNAs are poorly penetrated through the cell membrane, partially due to their uncharged property.
然而，与大多数DNA和RNA寡核苷酸不同，肽核酸的透膜能力很差，部分原因是由于它们具有不带电荷的性质。 - Until now, several methods have been developed to improve the intracellular delivery of antisense oligonucleotides.
到目前为止，已发展了数种提高寡聚核苷酸类化合物细胞内转运的方法。 - AimTo synthesize ribonucleoside-incorporated oligonucleotides and investigate their binding abilities with complementary sequences.
目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力。 - VEGF Antisense Oligonucleotides in Combination with DDP Inhibited the Growth of Osteosarcoma Nude Model
VEGF反义寡核苷酸与顺铂联合治疗抑制裸鼠骨肉瘤的生长 - Influence of osteopontin gene antisense oligonucleotides on bone and bones of passive smoking rats
骨桥蛋白基因反义寡核苷酸对被动吸烟大鼠骨组织的影响 - Antisense oligonucleotides block glucosylceramide synthase expression in breast cancer cells and its significance
反义寡核苷酸阻断乳腺癌细胞中葡萄糖神经酰胺合成酶的表达和意义 - Antisense oligonucleotides have been successfully employed to inhibit and modulate specifically gene expression.
反义寡聚核苷酸已成功用于对基因表达的特异性调控与抑制。 - Telomerase is a specialized reverse transcriptase that elongates the single-stranded chromosome ends and oligonucleotides in vivo and in vitro.
端粒酶是一种特殊的逆转录酶，它能在体内延伸染色体单链末端，在体外延伸寡聚核苷酸。一般认为端粒酶的蛋白催化亚基和RNA亚基组成了核心酶，它们对体外活性是必需的。 - Conclusion The liposome-mediated 99mTc-labeled antisense oligonucleotides could prohibit the cancer cells from growing and the oncogene from expressing.
结论脂质体介导的99mTc标记的反义寡核苷酸能抑制癌细胞的生长和癌蛋白的表？ - Oligonucleotides or peptide nucleic acid can form triplex-helical DNA by binding to specific sequences in double-stranded DNA of gene.
脱氧寡核苷酸或肽核酸可与基因双链DNA内的特定序列结合形成三链DNA，三链DNA结构的形成可以抑制靶基因的转录。 - Topical treatment with IL 20 and K16 antisense oligonucleotides can inhibit the expression of mRNA targeted.
IL20和K16反义寡核苷酸乳剂外涂可以抑制靶mRNA的水平及表达。