Protection of Onychin on Injury of Endothelium-Dependent Relaxtion Induced by Lysophosphatidylcholine 金粉蕨素对溶血性磷脂酰胆碱损伤血管内皮依赖性舒张功能的保护作用及机制
RESULT Onychin significantly decreased the growth inhibitory rate of injured endothelial cells, increased NO concentration in the medium and eNOS activity and up regulated phosph ERK1/ 2 expressing. 结果金粉蕨素保护组与损伤组相比,内皮细胞的生长抑制率明显降低,培养液中NO含量增高,eNOS活性增强,磷酸化ERK1/2表达上调。
Protective Effect of Onychin on Lipid Peroxidation in Experimental Liver Damage of Mice 金粉蕨素对小白鼠实验性肝损伤脂质过氧化的保护作用
METHODS The injured model was established by endothelial cell treated with menadione. Protective effect of onychin aganist growth inhibition of injured endothelial cell was determined by MTT assay and cell counting method; 方法以Menadione(O-2)损伤人脐静脉内皮细胞作为氧化损伤模型,采用MTT法和细胞计数法,观察不同浓度金粉蕨素对Menadione损伤内皮细胞生长抑制率的影响;