Objective: To investigate relationship of expression of the TH1/ TH2 cytokines to pathogenic mechanisms in murine autoimmune oophoritis. 目的:探讨TH1TH2型细胞因子的表达与自身免疫性卵巢功能损伤机理关系。
Becauce mZP3 protein was shown to possess at least two T cell epitopes and the capacity to induce T cell-mediated autoimmune oophoritis. 根据现有的研究表明:可能是在ZP3糖蛋白上至少有两个T细胞介导的抗原决定簇,诱发卵巢炎;