Patients with severe sensorineural deafness often have a certain extent damnification or degeneration of spiral ganglion neurons no matter what pathogeny is. Therefor, it is a challenge to recover the integrality of spiral ganglion neuron for otologist. 对于重度感音神经性耳聋的患者,不管导致疾病的诱因为何,一般都有不同程度的内耳螺旋神经节神经元的损伤或退化,所以如何恢复内耳螺旋神经节神经元的完整性为耳科学的一大挑战。