23 patients with neonatal hypoxic ischemic encephalopathy ( HIE) combined hypocalcemia was reported. The clinical manifestations except HIE's features are combined irregular, indefinite krauomania on the face and limbs; eyeball gaze ( periblepsis), fremitus, respiratory temporary arrest, and blood calcium descending. 本文报告了23例新生儿缺氧缺血性脑病(HIE)合并低钙血症,临床具有NIE表现又伴有面部和肢体不规则、不固定的节律性抽动、眼球凝视、震颤和有呼吸暂停及血钙下降等症状和体征。