Phenylbutyrate induced P-glycoprotein and BCRP expression and the efflux of drugs as determined with labeled substrates. 苯丁酸诱导P糖蛋白和BCRP的表达和药物的外向通量由标记底物来决定。
Effect of sodium phenylbutyrate and dimethylformamide on cell proliferation in breast carcinoma cell line 苯丁酸钠和二甲基甲酰胺对乳腺癌细胞增殖抑制影响的研究
Effects of sodium phenylbutyrate on invasive ability of human thyroid follicular carcinoma cell line and expression of MMP-9 and TIMP-1 苯丁酸钠对甲状腺滤泡癌细胞侵袭能力及MMP-9和TIMP-1表达的影响
Aim To determine the application of phenylbutyrate to differentiation therapy of hematological malignancies. 目的探讨苯丁酸钠在血液肿瘤诱导分化治疗中的应用方法。
Objective To observe the effect and the dosages of combined application of sodium phenylbutyrate ( SPB, a differentiation-inducing agent) and cisplatin ( a chemotherapeutic agent) on human glioma xenograft model. 目的探讨诱导分化剂苯丁酸钠与化疗药顺铂联合治疗可移植性人脑胶质瘤的剂量及疗效。
Methods RNA arbitrary primer differential display, SSCP, PCR product fast cloning, reverse Northern blot, sequencing and bioinformatics were used to study the differentiation of human glioma cell strain SHG 44 9 induced by Sodium Phenylbutyrate. 方法应用RNA随机引物差异显示、SSCP纯化、PCR产物快速克隆、反Northern杂交及生物信息学分析等方法,观察人脑胶质瘤细胞株SHG449分化过程中的基因表达变化。
Objective To study the mechanisms of proliferation-inhibiting effect of phenylbutyrate sodium ( SPB) on transplantable human glioma xenograft. 目的探讨苯丁酸钠对可移植性人脑胶质瘤增殖抑制作用机制。
Enantioselective Synthesis of Ethyl ( R)-2-Hydroxy-4-Phenylbutyrate Mediated by Saccharomyces cerevisiae in Organic Solvents 面包酵母催化溶剂相不对称还原合成(R)-2-羟基-4-苯基丁酸乙酯
Conclusion: Combined with neomycin and sodium phenylbutyrate has a great inhibitory effect on the glioma. 结论:新霉素和苯丁酸钠对胶质瘤细胞有抑制作用,联合用药抑制胶质瘤效果显著。
Phenylbutyrate inhibit proliferation in Kasumi-1 cells 苯丁酸钠对Kasumi-1细胞的生长抑制作用
Synergistic Anticancer Effect of Sodium Phenylbutyrate Combined with Nolatrexed Dihydrochloride in vitro 苯丁酸钠与盐酸洛拉曲克体外联合用药的抗癌增效作用观察
60 mg sodium phenylbutyrate be injected intraperitoneally, Bid. 苯丁酸钠60mgbid,腹腔注射。
Effects of sodium phenylbutyrate alone or in combination with fluorouracil or cisplatin on laryngeal carcinoma Hep-2 cell line 苯丁酸钠单用与氟尿嘧啶或顺铂联用对喉癌Hep-2细胞株的影响
Induced effect of sodium phenylbutyrate on laryngeal carcinoma Hep-2 cells in vitro 苯丁酸钠对喉癌Hep-2细胞株的体外诱导分化作用
Preliminary study on mechanisms of proliferation inhibition effect of phenylbutyrate sodium against transplantable human glioma xenograft 苯丁酸钠抑制可移植性人脑胶质瘤增殖机制的探讨
Kinetics of enantioselective hydrogenation to synthesize ethyl ( R)-2-hydroxy-4-phenylbutyrate 不对称合成(R)-2-羟基-4-苯基丁酸乙酯的动力学
Effect of phenylbutyrate, a histone deacetylase inhibitor, on differentiation and apoptosis of Kasumi-1 cells 脱乙酰化酶抑制剂苯丁酸钠体外诱导Kasumi1细胞分化和凋亡作用
The inhibitory effect of phenylbutyrate maybe relates the induction of apoptosis and cell differentiation. 苯丁酸钠诱导了细胞凋亡和细胞分化,使肿瘤细胞生长受抑。
Experimental research of differentiation-inducing therapy on human glioma xenograft by sodium phenylbutyrate 苯丁酸钠诱导分化治疗可移植性人脑胶质瘤实验研究
Conclusion Phenylbutyrate combined with other differentiation agents may be an effective differentiation therapy in a proportion of hematological malignancies. 结论苯丁酸钠和其它诱导分化剂联合应用可能是部分血液肿瘤有效的诱导分化治疗方法。
Objective To explore the blockade effect of phenylbutyrate ( PB), a histone deacetylase inhibitor, on the in vitro biological function of AML1/ ETO to reverse its transcription repression and induce Kasumi-1 cells to differentiate and apoptosis. 目的探讨组蛋白脱乙酰化酶抑制剂苯丁酸钠(PB)体外阻断AML1ETO的生物学功能,消除AML1ETO的转录抑制,诱导Kasumi1细胞生长抑制、分化和凋亡作用。
Neomycin Combined with Sodium Phenylbutyrate Inhibits the Growth of Glioma 新霉素联合苯丁酸钠对脑胶质瘤的抑制作用研究